China Factory Direct
|
|
| CAS number | 120-72-9 |
| Product name | Indole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Fragrance Industry | Synthesis of fragrance compounds | Chemical synthesis, esterification |
| Pharmaceutical Industry | Synthesis of drug intermediates | Cyclization, substitution |
| Pesticide Industry | Synthesis of plant growth regulators and insecticides | Oxidation, acylation |
| Dye Industry | Synthesis of dye intermediates | Condensation, coupling |
| Analytical Chemistry | Use as analytical reagent | Extraction and separation, spectroscopic analysis |
| Materials Industry | Synthesis of functional materials | Polymerization, grafting |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Indole Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase column (e.g., C18) and a UV detector (typically at 254 nm or 280 nm wavelength), with quantitative analysis performed by comparison to reference standards. This method offers high sensitivity and good reproducibility, suitable for purity and assay determination. |
| Gas Chromatography (GC) | Suitable for indole samples with good volatility. Typically uses an FID detector and quantifies after separation on a capillary column. Derivatization may be required to enhance volatility and stability. | |
| Purity Analysis | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes the characteristic absorption peak of indole near 280 nm, combined with a standard curve for purity estimation. Simple to operate, but lower specificity; suitable for preliminary screening. |
| Mass Spectrometry (MS or LC-MS) | Couples with liquid or gas chromatography to provide molecular weight and fragment ion information, used for structural confirmation and impurity identification. Offers high sensitivity and selectivity, ideal for trace impurity analysis. | |
| Residual Solvent Testing | Gas Chromatography (GC) | Detects residual organic solvents (e.g., methanol, ethanol, benzene) that may remain from manufacturing processes, in accordance with ICH guidelines. Headspace sampling is commonly used to improve accuracy and safety. |
| Moisture Content | Karl Fischer Titration | Accurately determines moisture content in samples, available in volumetric and coulometric methods. Essential for quality control of indole active pharmaceutical ingredients sensitive to moisture. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separates the main component from impurities using gradient elution, with impurity peaks identified via diode array detector (DAD) or mass spectrometry. Used to evaluate by-products from synthesis or degradation products. |
| Polymorphic Form Analysis | X-Ray Diffraction (XRD) | Analyzes the crystal structure of indole to determine the presence of polymorphism and ensure batch-to-batch consistency. |
| Differential Scanning Calorimetry (DSC) | Measures melting temperature and thermal behavior, aiding in the identification of crystalline forms and assessment of purity. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (GC) |
| Melting Point | 52.0–54.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.