(R)-(+)-1,2-Dithiolane-3-pentanoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1200-22-2 |
| Product name | (R)-(+)-1,2-Dithiolane-3-pentanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(+)-1,2-Dithiolane-3-pentanoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antioxidant; treatment of diabetic peripheral neuropathy | Used as an active pharmaceutical ingredient (API) in the synthesis of neurotherapeutic drugs, administered orally or via injection |
| Dietary Supplements | Nutritional supplementation; anti-aging support | Incorporated into capsules, tablets, and other dietary supplements to scavenge free radicals and support cellular energy metabolism |
| Cosmetics | Anti-aging skincare ingredient | Incorporated into facial creams, serums, and other skincare products to mitigate oxidative skin damage through its antioxidant activity |
| Biochemical Research | Chiral reagent; enzymatic cofactor | Applied in laboratory studies of mitochondrial metabolism and oxidative stress mechanisms, and used as a model compound for coenzyme studies |
Manufacturing Quality Control of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | By measuring the infrared absorption spectrum of the sample and comparing it with a reference spectrum, the characteristic functional groups and structure of R-(+)-lipoic acid are confirmed. |
| Specific Rotation Determination | Using a polarimeter to measure the optical rotation of the sample at a specific wavelength (typically the sodium D line, 589 nm) and temperature, to verify its optical purity and R-configuration. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Utilizing a reverse-phase C18 column with an appropriate mobile phase (e.g., methanol-water or acetonitrile-buffer system) for separation, and quantifying the main component using a UV detector (typically at 200–210 nm). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using gradient or isocratic elution to separate and detect potential process-related impurities or degradation products (e.g., S-enantiomer, oxidation products), with impurity content calculated by area normalization or self-reference methods. |
| Optical Purity / Enantiomeric Excess | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employing a chiral stationary phase column (e.g., cyclodextrin- or polysaccharide-derived) to effectively resolve the R-(+)- and S-(−)-lipoic acid enantiomers, evaluating enantiomeric purity (typically requiring ee ≥ 98%). |
| Drying Loss | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Drying the sample at a specified temperature (e.g., 60–80°C) for a defined period and measuring the mass loss to assess moisture and volatile substance content. |
| Residue on Ignition | High-Temperature Ashing Method | Incinerating the sample at high temperature (typically 700–800°C) to constant weight to determine the content of inorganic residues, controlling levels of inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measuring concentrations of heavy metal elements such as lead, arsenic, cadmium, and mercury using atomic absorption or inductively coupled plasma mass spectrometry, ensuring compliance with pharmacopoeial limits. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection with a capillary column for separation, and quantifying residual organic solvents (e.g., methanol, acetone, dichloromethane) potentially present from manufacturing using FID or MS detectors. |
Technical Specifications of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC) |
| Optical Rotation | +110 to +121 deg (c=1, in chloroform) |
| Melting Point | 48 to 52 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Safety Information of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Industrial (R)-(+)-1,2-Dithiolane-3-pentanoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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