tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1201187-44-1 |
| Product name | tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of kinase inhibitors | Organic synthesis, coupling reactions |
| Biochemistry | Probe or tool compound for protein kinase research | Biological activity testing, molecular labeling |
| Drug Discovery | Candidate compound for developing antitumor or anti-inflammatory agents | Molecular structure modification, structure–activity relationship (SAR) studies |
Manufacturing Quality Control of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state of the sample (e.g., white to off-white powder) and check for visible foreign matter. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare the sample spectrum with a reference standard to confirm consistency of characteristic functional group absorption peaks (e.g., C=O, N-H, S=O). |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze chemical shifts, integration areas, and coupling constants in hydrogen and carbon spectra; compare with theoretical structure to confirm molecular identity. | |
| Purity/Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column and UV detector (typically at 254 nm or 280 nm); calculate purity by peak area normalization or external standard method. |
| Impurity Analysis | HPLC-UV or LC-MS | Detect related substances (e.g., starting materials, intermediates, degradation products) using gradient elution to separate impurities and assess individual impurity levels. |
| Water Content | Karl Fischer Titration | Precisely determine trace moisture in organic compounds; applicable via volumetric or coulometric methods to ensure the sample meets required dryness specifications. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, dichloromethane, ethyl acetate) according to ICH guidelines. |
| Melting Point | Melting Point Apparatus | Determine initial and final melting temperatures using capillary method to assess crystalline purity and batch-to-batch consistency. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect toxic elemental impurities such as lead, cadmium, mercury, and arsenic; ensure compliance with pharmacopeial or ICH Q3D limits. |
| Sulfated Ash / Residue on Ignition | Sulfated Ashing Method | Sample is treated with sulfuric acid and then ignited at high temperature; residue is weighed to estimate total inorganic impurities. |
| Crystal Form Analysis | X-Ray Diffraction (XRD) | Analyze the crystal structure of solid samples to identify polymorphic forms and ensure batch-to-batch consistency (where applicable). |
| Particle Size Distribution | Laser Diffraction Analysis (LDA) | Measure particle size and distribution for solid dosage precursors, which affects solubility and downstream formulation processes. |
Technical Specifications of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 218-222°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Industrial tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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