China Factory Direct
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| CAS number | 1205-72-7 |
| Product name | 4-AMINO-1-BENZYLPIPERIDINE DIHYDROCHLORIDE HYDRATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of opioid analgesics (e.g., fentanyl and its derivatives) | Piperidine ring introduced via reductive amination or nucleophilic substitution, followed by acylation, alkylation, and other steps to construct the target molecular scaffold |
| Pharmaceutical R&D | Used to build benzylpiperidine-containing bioactive compound libraries for screening novel central nervous system (CNS) drugs | Solid-phase or liquid-phase parallel synthesis employed, combined with structural modifications to optimize potency and selectivity |
| Organic Synthesis | Nitrogen-containing heterocyclic building block for multicomponent coupling reactions to construct complex molecular frameworks | Acts as a nucleophile in C–N bond formation under palladium-catalyzed cross-coupling or photoredox catalytic conditions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against reference standard calibration curve. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethanol, acetone) against certified standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using plasma emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine total chloride from hydrochloride salt form. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a defined aqueous suspension or solution using calibrated pH electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature incineration (700-800 C) to determine inorganic ash content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and specified viewing conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral compound in solution, expressed as degrees per dm/g/mL. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic bacteria and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.