China Factory Direct
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| CAS number | 121-60-8 |
| Product name | N-Acetylsulfanilyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of sulfonamide antibiotic intermediates | Used as a key intermediate in the preparation of sulfonamide drugs such as sulfacetamide and sulfapyridine, introducing the sulfonamide group via amidation and condensation reactions |
| Dyes | Synthesis of organic pigments and dyes | Involved in the synthesis of azo dyes and functional dyes, constructing the dye molecular backbone through electrophilic substitution or coupling reactions |
| Pesticides | Intermediates for fungicides and plant growth regulators | Employed in synthesizing sulfonamide-containing agrochemicals, undergoing substitution or cyclization reactions under specific catalytic conditions |
| Fine Chemicals | Functional additives and polymer modifiers | Acts as a sulfonyl chloride donor for polymer modification or surfactant synthesis, introducing hydrophilic groups via reactions with alcohols or amines |
| Test Item | Common Testing Method | Method Overview |
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| Purity Test | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase column with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (e.g., 220 nm or 254 nm) to quantify the purity of the main component. Suitable for rapid and accurate assessment of target compound content and impurity levels in samples. |
| Assay | Titration (non-aqueous or acid-base titration) | Leverages the reaction of the acyl chloride group with a standard base solution (e.g., sodium hydroxide or potassium tert-butoxide), determining the assay via potentiometric titration or indicator method. Simple to perform and ideal for rapid control during manufacturing processes. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Separates and identifies volatile or derivatizable impurities; structural identification of unknown impurities is achieved through mass spectral library matching. Particularly suitable for analysis of residual solvents or by-products. |
| Moisture Content | Karl Fischer Titration | Determines trace moisture using volumetric or coulometric methods to prevent hydrolysis of the acyl chloride group, thereby ensuring product quality and stability. |
| Appearance and Physical Characteristics | Visual Inspection + Melting Point Determination | Observe color and physical state (typically white to light yellow crystals), and determine melting range using a melting point apparatus to assess whether physical properties meet specifications (literature melting point approximately 148–150°C). |
| Free Acid / Free Chloride Content | Ion Chromatography (IC) or Colorimetric Method | Detects by-products such as p-acetamidobenzenesulfonic acid or hydrochloric acid generated from hydrolysis, evaluating product stability and adequacy of storage conditions. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Quantitatively analyzes organic solvents possibly remaining from the manufacturing process (e.g., dichloromethane, toluene), ensuring compliance with ICH Q3C limits. |
| Stability Testing (Accelerated/Long-term) | Periodic HPLC Monitoring | Samples are stored under specified temperature and humidity conditions, and periodically analyzed by HPLC to monitor changes in the active ingredient and formation of degradation products, assessing shelf life and appropriate storage conditions. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.