China Factory Direct
|
|
| CAS number | 121-66-4 |
| Product name | 2-Amino-5-nitrothiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the synthesis of sulfonamide antibacterial agents (e.g., sulfathiazole) | Serves as the core scaffold; sulfonamide functionality is introduced via diazotization-coupling or direct condensation with sulfonamide precursors |
| Pharmaceutical Industry | Intermediate in the synthesis of antitubercular and antithyroid drugs | The amino group on the thiazole ring undergoes acylation or alkylation to construct the drug molecule backbone |
| Dye Industry | Intermediate in the synthesis of azo and sulfur dyes | The amino group is diazotized to form a diazonium salt, followed by coupling with aromatic amines or phenols to produce azo dyes |
| Agrochemical Industry | Raw material for synthesizing fungicides and agrochemical derivatives | Chemical modification of the amino group or condensation with organophosphorus or heterocyclic compounds yields fungicidally active agrochemical molecules |
| Chemical R&D | Organic synthesis reagent and building block for novel heterocyclic compounds | Functions as a nitro-substituted thiazole scaffold, participating in reduction and nucleophilic substitution reactions to generate precursors for functional materials |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and condition (usually a light yellow to yellow crystalline powder) under natural light or standard light source. |
| Identification | Infrared Spectroscopy (IR) | Determine characteristic absorption peaks using an infrared spectrometer and compare with standard spectra to confirm structure. |
| High-Performance Liquid Chromatography (HPLC) | Identify by comparing retention time with reference substance using HPLC. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 chromatography column, with appropriate mobile phase (such as methanol-water or acetonitrile-buffer salt system), isocratic or gradient elution, and UV detector (typically around 254 nm) for quantitative analysis of the main component content. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect and quantify possible synthetic by-products, degradation products, etc., using high-resolution HPLC conditions. Typically use area normalization method or main component self-reference method with correction factors. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry at a specified temperature (e.g., 105°C) until constant weight, calculate the percentage of mass loss to evaluate moisture and volatile matter content. |
| Melting Point | Melting Point Determination Method | Determine the melting temperature range using a melting point apparatus, and compare it with literature values (approximately 163–165°C) to judge purity. |
| Residual Solvents | Gas Chromatography (GC) | Determine residual organic solvents (e.g., methanol, ethanol, dichloromethane, etc.) used in production using GC with headspace or direct injection and FID detector. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic after digesting the sample, ensuring compliance with pharmacopoeia or regulatory limits. |
| pH Value (If Dissolved in Solution) | pH Meter Measurement Method | Dissolve the sample into a certain concentration aqueous solution and measure its acidity or alkalinity using a calibrated pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 145–149°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.