Ethyl 6-Methyl-5-nitronicotinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1211538-09-8 |
| Product name | Ethyl 6-Methyl-5-nitronicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 6-Methyl-5-nitronicotinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 6-Methyl-5-nitronicotinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 6-Methyl-5-nitronicotinate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of targeted therapeutics, such as kinase inhibitors | Applied in drug discovery to construct molecular scaffolds via coupling and cyclization reactions |
| Research | Used as an organic synthesis intermediate for laboratory-scale studies | Applied in the synthesis and functionalization of heterocyclic compounds, including preparation of pyridine derivatives |
| Chemicals | Used in the synthesis of complex organic molecules, such as functional materials or fine chemicals | Applied to introduce functional groups through reaction steps including nitration and esterification |
Manufacturing Quality Control of Ethyl 6-Methyl-5-nitronicotinate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification of structurally related impurities (e.g., starting materials, intermediates, degradants) using gradient elution and UV or mass spectral detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg, Ni) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration using iodine generated in situ to determine trace water content based on stoichiometric reaction with water. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of physical state and color intensity compared to standardized platinum-cobalt (APHA) reference solutions. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (500–600 °C) and weighing. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral, but method included for potential enantiomeric contaminants). |
Technical Specifications of Ethyl 6-Methyl-5-nitronicotinate
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 6-Methyl-5-nitronicotinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 6-Methyl-5-nitronicotinate
Safety Information of Ethyl 6-Methyl-5-nitronicotinate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 6-Methyl-5-nitronicotinate
Industrial Ethyl 6-Methyl-5-nitronicotinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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