China Factory Direct
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| CAS number | 1214196-85-6 |
| Product name | 1-Boc-2-Piperazinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate for synthesizing biologically active piperazine derivatives | Employed in organic synthesis to construct target molecular frameworks via deprotection, amidation, or alkylation reactions |
| Pharmaceutical Manufacturing | Used to prepare precursors for antiviral, anticancer, or central nervous system drugs | Serves as a key building block in multistep synthetic routes, commonly applied for structural modification in solid-phase or solution-phase peptide synthesis |
| Chemical Research | Used as a synthon for constructing complex nitrogen-containing heterocyclic compounds | Enables selective functional group transformations under mild conditions through Boc-protecting group modulation |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generation to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, etc.) after acid digestion, with detection at sub-pptr levels. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution following sample dissolution and filtration. |
| Sulfate Content | Ion Chromatography | Quantification of sulfate anions via suppressed conductivity detection after sample preparation and dilution. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a sodium D-line polarimeter to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample by light scattering to report D10, D50, D90 values per USP <429>. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after heating under controlled temperature and vacuum to determine volatile and moisture content. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode and buffer references. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.