Methyl 2-bromo-4-(trifluoromethyl)benzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1214334-90-3 |
| Product name | Methyl 2-bromo-4-(trifluoromethyl)benzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 2-bromo-4-(trifluoromethyl)benzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 2-bromo-4-(trifluoromethyl)benzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 2-bromo-4-(trifluoromethyl)benzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including anticancer agents and kinase inhibitors | Introduces aryl or alkenyl groups via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) under inert atmosphere; or constructs target molecular scaffolds through functional group transformations such as hydrolysis and aminolysis |
| Pesticide R&D | Used to synthesize novel trifluoromethyl-containing insecticidal and fungicidal candidate compounds | Serves as a structural building block in heterocycle construction (e.g., condensation with hydrazides or amidines to form nitrogen-containing heterocycles such as triazoles and pyrimidines), or enables selective introduction of functional side chains via bromine substitution |
| Materials Science | Monomer for electron-transport/hole-blocking materials in organic light-emitting diode (OLED) devices | Converted into pinacol boronate esters or iodo derivatives via lithiation-borylation or direct halogen exchange, then incorporated into conjugated polymer backbones via Suzuki or Ullmann coupling |
Manufacturing Quality Control of Methyl 2-bromo-4-(trifluoromethyl)benzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine-based reagent to determine trace water content in the sample. |
| Acid Value | Acid-Base Titration | Titration with standardized potassium hydroxide solution to measure free carboxylic acid groups, if hydrolysis occurs. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after microwave-assisted acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions following sample dissolution and dilution in aqueous matrix. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after cooling in desiccator. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm chiral purity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values per ISO 13320. |
| Bulk and Tapped Density | Tap Density Tester | Measurement of mass per unit volume before and after mechanical tapping to assess flowability and compressibility. |
Technical Specifications of Methyl 2-bromo-4-(trifluoromethyl)benzoate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Refractive Index (n20/D) | 1.525–1.535 |
| Relative Density (20°C/25°C) | 1.48–1.52 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 2-bromo-4-(trifluoromethyl)benzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 2-bromo-4-(trifluoromethyl)benzoate
Safety Information of Methyl 2-bromo-4-(trifluoromethyl)benzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 2-bromo-4-(trifluoromethyl)benzoate
Industrial Methyl 2-bromo-4-(trifluoromethyl)benzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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