Methyl 5-broMo-6-chloropyridine-2-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1214353-79-3 |
| Product name | Methyl 5-broMo-6-chloropyridine-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 5-broMo-6-chloropyridine-2-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 5-broMo-6-chloropyridine-2-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 5-broMo-6-chloropyridine-2-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides | Used to synthesize pyridine-based insecticides exhibiting nicotinic acetylcholine receptor agonist activity (e.g., flupyradifurone analogues) via multi-step reactions including hydrolysis, amination, and cyclization to construct the key pharmacophore |
| Pharmaceuticals | Intermediate for anticancer and antiviral drug candidates | Employed in constructing heterocyclic scaffolds of kinase inhibitors or nucleoside analogues, typically involving transition-metal-catalyzed reactions such as Suzuki coupling and Buchwald–Hartwig amination to introduce substituents |
| Materials Science | Monomer for organic optoelectronic functional materials | Serves as a building block for electron-transporting small molecules or polymers, applied in OLED emissive layers or interfacial modification layers of perovskite solar cells, prepared via halogen exchange or direct coupling polymerization |
Manufacturing Quality Control of Methyl 5-broMo-6-chloropyridine-2-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., regioisomers, hydrolysis/degradation products) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, dichloromethane) using headspace GC with flame ionization detection and internal standard calibration. |
| Heavy Metals | ICP-MS | Determines total elemental impurities (e.g., Pb, Cd, Ni, As) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration | Quantifies water by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ion (from potential hydrolysis or residual HCl) using suppressed conductivity detection with anion-exchange column. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities affecting lattice integrity. |
| Appearance & Color | Visual Inspection / Hazen Color Scale | Evaluates physical state (crystalline powder), homogeneity, and color intensity against standardized platinum-cobalt scale under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual non-volatile matter. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral purity and absence of racemization (though compound is achiral, detects chiral contaminants). |
Technical Specifications of Methyl 5-broMo-6-chloropyridine-2-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to structure |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 5-broMo-6-chloropyridine-2-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 5-broMo-6-chloropyridine-2-carboxylate
Safety Information of Methyl 5-broMo-6-chloropyridine-2-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 5-broMo-6-chloropyridine-2-carboxylate
Industrial Methyl 5-broMo-6-chloropyridine-2-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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