China Factory Direct
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| CAS number | 121505-93-9 |
| Product name | BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate for constructing peptide-based and small-molecule therapeutics | Acts as a glycine derivative in solid-phase or solution-phase peptide synthesis to form amide bonds; commonly employed to introduce Weinreb amide motifs, enabling subsequent reaction with Grignard or organolithium reagents to generate aldehydes or ketones |
| Organic Synthesis | Weinreb amide building block for controlled carbonyl functional group transformations | Amino group protected with N-BOC to enhance reaction selectivity; the N-methoxy-N-methylamide moiety reacts with nucleophiles (e.g., organometallic reagents) to deliver aldehydes in high yield while suppressing over-addition |
| Biochemical Research | Synthesis of probes or labeled molecules containing modified glycine residues | Acid-labile BOC protecting group enables selective deprotection under mild conditions for controlled coupling; the Weinreb amide moiety allows further derivatization to incorporate fluorescent or biotin tags |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specified wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on iodine consumption in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by weight determination of residual residue. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and identity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a defined aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension via angular scattering pattern of laser beam. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.