tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1215071-17-2 |
| Product name | tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in synthesizing fluorinated piperidine-containing drug molecules, such as antiviral or neurological disorder candidate compounds | Serves as a key building block in multistep organic synthesis, commonly employed in deprotection and functional group transformations to construct the target molecular scaffold |
Manufacturing Quality Control of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at specified wavelength based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by retention time and peak area relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., THF, ethyl acetate) via headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Measures trace metal impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Residual Palladium | ICP-OES | Quantifies palladium residue from catalytic synthesis steps via high-temperature plasma excitation and optical emission detection. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and identity. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry or wet dispersion using angular scattering pattern of laser beam. |
| Loss on Drying | Gravimetric Method | Determines volatile content by measuring weight loss after controlled heating under specified conditions. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
Safety Information of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
Industrial tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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