S-3-CBZ-AMINO PYRROLIDINE-HCl Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1217631-74-7 |
| Product name | S-3-CBZ-AMINO PYRROLIDINE-HCl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for S-3-CBZ-AMINO PYRROLIDINE-HCl
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk S-3-CBZ-AMINO PYRROLIDINE-HCl Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of S-3-CBZ-AMINO PYRROLIDINE-HCl
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing drug molecules containing a pyrrolidine ring (e.g., DPP-4 inhibitors for diabetes treatment) | Used as chiral building blocks in coupling reactions, amino protection/deprotection, and subsequent cyclization steps |
| Pharmaceutical R&D | Construction of candidate compound libraries featuring an (S)-pyrrolidine motif | Employed as a structural diversification unit in high-throughput screening, modified via palladium-catalyzed cross-coupling or reductive amination |
Manufacturing Quality Control of S-3-CBZ-AMINO PYRROLIDINE-HCl
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, relative to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection, comparing retention times and peak areas of (S)- and (R)-enantiomers. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to quantify water via stoichiometric redox reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection, quantifying common solvents (e.g., MeOH, EtOAc, toluene) against calibration standards. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion, measuring metals such as Pb, Cd, Hg, As, and Ni at trace levels. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on AgCl precipitation potential change. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., de-benzylated, racemized, or hydrolyzed by-products) using gradient HPLC. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against defined standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which the crystalline solid transitions to liquid, using calibrated capillary apparatus. |
| Loss on Drying | Gravimetric Analysis | Measurement of mass loss after drying under specified vacuum/temperature conditions, indicating volatile content including residual solvents and moisture. |
| pH of Solution | pH Meter | Measurement of aqueous suspension or solution pH using calibrated glass electrode, reflecting acidic character from HCl salt form. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms following filtration, incubation, and colony counting per pharmacopeial guidelines. |
Technical Specifications of S-3-CBZ-AMINO PYRROLIDINE-HCl
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C - 152°C |
| Optical Rotation | +28.5° to +31.5° (c=1, in 1M HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of S-3-CBZ-AMINO PYRROLIDINE-HCl
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of S-3-CBZ-AMINO PYRROLIDINE-HCl
Safety Information of S-3-CBZ-AMINO PYRROLIDINE-HCl
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of S-3-CBZ-AMINO PYRROLIDINE-HCl
Industrial S-3-CBZ-AMINO PYRROLIDINE-HCl Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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