2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 122111-01-7 |
| Product name | 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 122111-01-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 122111-01-7 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 122111-01-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate in gemcitabine synthesis | Serves as a key precursor in the chemical synthesis of the anticancer drug gemcitabine, with final product formation achieved via hydrolysis, amination, and subsequent steps |
| Organic Synthesis | Building block for nucleoside compound synthesis | Used to construct modified ribose scaffolds; participates in glycosylation reactions at laboratory scale to prepare novel nucleoside analogs |
Manufacturing Quality Control of 122111-01-7
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR are used to confirm molecular structure, particularly the position of fluorine atoms, sugar ring configuration, and the linkage site of the cinnamoyl ester group. Structural accuracy is verified through chemical shifts, coupling constants, and peak shapes. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Reverse-phase chromatography columns (e.g., C18) are used with mobile phases of methanol/water or acetonitrile/water, detected by UV detector (UV 254 nm). This method separates the main component from impurities and quantifies purity, typically requiring ≥98%. |
| Molecular Weight Determination | Mass Spectrometry (MS, ESI-TOF or LC-MS) | Electrospray ionization mass spectrometry (ESI-MS) or time-of-flight mass spectrometry (TOF-MS) is used for precise molecular weight determination, confirming molecular formula (e.g., [M+H]⁺ ion peak), supporting structural elucidation. |
| Residual Solvent Testing | Gas Chromatography (GC) | Headspace or direct injection is employed using capillary columns (e.g., DB-624), with FID or MS detection. It detects organic solvents (e.g., acetonitrile, toluene, dichloromethane) potentially remaining from synthesis, complying with ICH Q3A guidelines. |
| Water Content | Karl Fischer Titration | Applicable to compounds containing polar functional groups, this method accurately measures water content in samples to prevent impacts on stability or subsequent reactions. |
| Content Assay | UV-Visible Spectrophotometry (UV-Vis) | Quantitative analysis based on characteristic absorption peaks of the compound at specific wavelengths (e.g., 254–270 nm), requiring calibration curve establishment; suitable for rapid preliminary screening. |
| Polymorphism Analysis | X-Ray Diffraction (XRD) | Used to determine the presence of polymorphic forms, especially for solid drug substances, aiding in assessing crystal form stability and understanding differences in solubility and bioavailability. |
| Thermal Analysis | Differential Scanning Calorimetry (DSC) | Used to detect melting temperature, crystallization behavior, and thermal stability, identifying decomposition peaks or phase transitions, supporting quality consistency evaluation. |
| Impurity Profiling | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) | Enables high-sensitivity detection of trace impurities, including synthetic by-products, degradation products, or isomers. Useful for comprehensive impurity profiling and setting acceptable limits. |
Technical Specifications of 122111-01-7
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148.0 to 152.0 °C |
| Optical Rotation | +69.0 to +73.0° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 122111-01-7
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 122111-01-7
Packaging of 122111-01-7
Industrial 122111-01-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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