(S)-3-AMINO-1-CBZ-PYRROLIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 122536-72-5 |
| Product name | (S)-3-AMINO-1-CBZ-PYRROLIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-3-AMINO-1-CBZ-PYRROLIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-3-AMINO-1-CBZ-PYRROLIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-3-AMINO-1-CBZ-PYRROLIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Chiral Drug Intermediates | Serves as a key chiral building block in the synthesis of chiral active pharmaceutical ingredients (APIs), including antibiotics, antiviral agents, and receptor antagonists. |
| Pharmaceutical Chemicals | Combinatorial Chemistry and Library Synthesis | Applied in constructing heterocyclic compound libraries with potential biological activity for drug screening, leveraging the pyrrolidine ring scaffold. |
| Organic Synthesis | Asymmetric Synthesis | Used as a chiral source or ligand precursor in asymmetric catalytic reactions or in the synthesis of organometallic compounds to introduce chiral centers. |
| Research Reagents | Laboratory R&D | Employed in small-scale synthesis, process route development, and structural confirmation during pharmaceutical R&D. |
Manufacturing Quality Control of (S)-3-AMINO-1-CBZ-PYRROLIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation and quantification of (S)- and (R)-enantiomers using a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, Ni) after acid digestion, with detection limits <1 ppb. |
| Residual Chlorides | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharp melting range indicates crystalline purity and identity. |
| Appearance and Color | Visual Inspection / Hazen Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared to platinum-cobalt standards. |
| Specific Optical Rotation | [α]D Measurement | Determination of rotation angle of plane-polarized light at 589 nm to confirm chiral integrity and concentration-normalized specific rotation. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., deprotected amine, hydrolyzed ester, diastereomers) under stressed conditions. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave digestion, using plasma emission at characteristic wavelengths (e.g., 224.48 nm). |
Technical Specifications of (S)-3-AMINO-1-CBZ-PYRROLIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Optical Rotation | +24.0° to +26.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-3-AMINO-1-CBZ-PYRROLIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-3-AMINO-1-CBZ-PYRROLIDINE
Safety Information of (S)-3-AMINO-1-CBZ-PYRROLIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-3-AMINO-1-CBZ-PYRROLIDINE
Industrial (S)-3-AMINO-1-CBZ-PYRROLIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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