China Factory Direct
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| CAS number | 122536-76-9 |
| Product name | (S)-3-(Boc-amino)pyrrolidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for certain antibiotics or antiviral drugs | Prepared via organic synthesis methods, including condensation and cyclization |
| Biochemistry | Intermediate for synthesizing amino acid derivatives or peptide compounds | Used as an amino-protecting group in peptide synthesis |
| Polymers | Synthesis of specialty functional polymeric materials | Employed as a monomer or crosslinking agent in polymerization reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation on a chiral stationary phase followed by UV detection to quantify (S)-enantiomer excess relative to racemate. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of Pb, Cd, Hg, As, and other regulated metals at sub-ppb levels. |
| Residual Palladium | ICP-OES | Plasma emission spectroscopy after acid digestion to measure palladium residues from catalytic hydrogenation steps. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract to assess residual HCl or Boc-Cl-derived impurities. |
| Related Substances | HPLC-UV | Gradient HPLC method to separate and quantify structurally related impurities including de-Boc product, diastereomers, and hydrolysis by-products. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 deg C and 589 nm to confirm chiral integrity and concentration. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion laser diffraction analysis to characterize bulk handling and dissolution behavior. |
| Microbial Limits | Membrane Filtration | Aerobic microbial count and absence-of-pathogens testing per USP <61> and <62> using membrane filtration and culture methods. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -22.0 to -19.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.