3-Nitro-4-trifluoromethylbenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1227489-72-6 |
| Product name | 3-Nitro-4-trifluoromethylbenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Nitro-4-trifluoromethylbenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Nitro-4-trifluoromethylbenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Nitro-4-trifluoromethylbenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides | Synthesized into neonicotinoid or anthranilamide insecticidal active ingredients featuring trifluoromethyl and nitro substituents, via reductive cyclization or cross-coupling to construct the heterocyclic core |
| Pharmaceuticals | Intermediate for anticancer and anti-inflammatory drug candidates | Employed as a trifluoromethyl-substituted aryl nitrile building block in Suzuki coupling, nitrile hydrolysis/ammonolysis, and related transformations to assemble kinase inhibitor or TLR modulator scaffolds |
| Materials Science | Precursor for organic optoelectronic functional materials | Used to synthesize high-electron-affinity n-type semiconductor small molecules or polymers; conjugated acceptor units are incorporated via Knoevenagel condensation or Stille coupling for application in OLED electron transport layers or OPV acceptor materials |
Manufacturing Quality Control of 3-Nitro-4-trifluoromethylbenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, methanol, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfate Impurity | Ion Chromatography | Quantification of sulfate ions via ion chromatography with conductivity detection following sample dissolution. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against white/black background. |
| Bulk Density | USP <616> Tap Density Method | Measurement of mass per unit volume after standardized tapping of a known mass in a graduated cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution by measuring angular variation in laser light scattering from dispersed particles in air or liquid. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing (700-800 C) of sample in platinum crucible. |
Technical Specifications of 3-Nitro-4-trifluoromethylbenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Nitro-4-trifluoromethylbenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Nitro-4-trifluoromethylbenzonitrile
Safety Information of 3-Nitro-4-trifluoromethylbenzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Nitro-4-trifluoromethylbenzonitrile
Industrial 3-Nitro-4-trifluoromethylbenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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