2-chloro-3-fluoropyridin-4-aMine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1227577-03-8 |
| Product name | 2-chloro-3-fluoropyridin-4-aMine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-chloro-3-fluoropyridin-4-aMine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-chloro-3-fluoropyridin-4-aMine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-chloro-3-fluoropyridin-4-aMine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anticancer, antiviral, or neurosystem-related drugs | Integrated into the target molecular scaffold via organic synthesis steps such as nucleophilic substitution, coupling reactions, or reductive amination |
| Agrochemicals | Employed as a structural building block for agrochemical active ingredients, particularly in fluorinated pyridine-based insecticides or herbicides | Prepared through processes including halogen exchange, amino group protection/deprotection, and ring system functionalization |
| Materials Science | Applied as a functionalized ligand or precursor for constructing metal–organic frameworks (MOFs) or optoelectronic materials | Amino and halogen sites participate in crosslinking or complexation structure formation via coordination chemistry or polymerization reactions |
Manufacturing Quality Control of 2-chloro-3-fluoropyridin-4-aMine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., regioisomers, dehalogenated by-products) using gradient elution and UV/MS detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DMF, THF, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, achieving sub-ppt detection limits. |
| Chloride Ion (Inorganic Salt Impurity) | Ion Chromatography (IC) with Conductivity Detection | Separation of chloride anions on an anion-exchange column and quantification via suppressed conductivity detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, indicating crystallinity and identity. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at sodium D-line (589 nm) to confirm chiral purity if applicable (though compound is achiral, used for batch consistency). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values per ISO 13320, relevant for downstream processing. |
| Bulk and Tapped Density | ASTM D6393 | Gravimetric measurement of mass per unit volume before and after standardized mechanical tapping to assess flowability and compressibility. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 10 mg/mL in water) to detect acidic/basic degradation products or residual reagents. |
| Organic Volatile Impurities (e.g., Chlorinated Solvents) | GC-ECD | Gas chromatographic separation with electron capture detection for highly sensitive quantification of chlorinated contaminants (e.g., chloroform, dichloromethane). |
Technical Specifications of 2-chloro-3-fluoropyridin-4-aMine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-chloro-3-fluoropyridin-4-aMine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-chloro-3-fluoropyridin-4-aMine
Safety Information of 2-chloro-3-fluoropyridin-4-aMine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-chloro-3-fluoropyridin-4-aMine
Industrial 2-chloro-3-fluoropyridin-4-aMine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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