D-4-Fluorophenylalanine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 122839-52-5 |
| Product name | D-4-Fluorophenylalanine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-4-Fluorophenylalanine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-4-Fluorophenylalanine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-4-Fluorophenylalanine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Unnatural amino acids for synthesizing fluorinated peptides and proteins in protein engineering studies | Used as building blocks in solid-phase peptide synthesis (SPPS) to introduce fluorine atoms, enhancing metabolic stability or modulating pharmacokinetic properties |
| Biochemical Research | Isotope-labeled precursors (e.g., 19F NMR probes) for analyzing protein structure and dynamics | Prepared via enzymatic transformation or chemical synthesis for 19F-labeled proteins; supplemented as an amino acid in cell-free protein expression systems |
| Diagnostics Reagent Development | Potential intermediate for PET/MRI dual-modality probe molecules (requiring further derivatization) | Modified via diazotization–fluoroborate displacement or nucleophilic aromatic substitution (SNAr), followed by conjugation with radionuclides or contrast agents |
Manufacturing Quality Control of D-4-Fluorophenylalanine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Resolves enantiomers on a chiral stationary phase; D-isomer content determined by peak area ratio relative to total amino acid peaks. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., des-fluoro analog, diastereomers) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Potentiometric Titration | Determines chloride ion concentration by titration with silver nitrate using a silver/silver chloride electrode for endpoint detection. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Measures hydrogen ion activity in a standardized aqueous solution using calibrated glass electrode pH meter. |
| Specific Optical Rotation | [alpha]D Measurement | Determines chiral integrity by measuring rotation of plane-polarized light at 589 nm using a digital polarimeter. |
| Loss on Drying | Gravimetric Analysis | Quantifies volatile matter by weight loss after drying under controlled temperature and vacuum conditions. |
| Residue on Ignition | Sulfated Ash Test | Measures inorganic residue after high-temperature combustion in presence of sulfuric acid, expressed as sulfate ash. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) using filtration, culture, and colony enumeration. |
Technical Specifications of D-4-Fluorophenylalanine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C |
| Optical Rotation | +9.5 to +11.5° (c=1, 1M HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-4-Fluorophenylalanine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-4-Fluorophenylalanine hydrochloride
Safety Information of D-4-Fluorophenylalanine hydrochloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of D-4-Fluorophenylalanine hydrochloride
Industrial D-4-Fluorophenylalanine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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