(R)-2-(1-aMinoethyl)-4-chlorophenol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1228571-53-6 |
| Product name | (R)-2-(1-aMinoethyl)-4-chlorophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-2-(1-aMinoethyl)-4-chlorophenol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-2-(1-aMinoethyl)-4-chlorophenol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-2-(1-aMinoethyl)-4-chlorophenol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of selective β3-adrenergic receptor agonists (e.g., mirabegron) | Multi-step organic synthesis, including asymmetric synthesis or chiral resolution to obtain the (R)-configuration, followed by functional group transformations of the amine and phenolic hydroxyl groups |
| Pharmaceutical R&D | Applied in the development of candidate drugs for overactive bladder (OAB) | Employed as a key chiral building block in drug molecule construction, participating in reaction steps such as amidation and alkylation |
Manufacturing Quality Control of (R)-2-(1-aMinoethyl)-4-chlorophenol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 275 nm, comparing peak area to calibrated standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and calculates ee from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration using iodine generated in situ via electrochemical reaction. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) by mass spectrometric detection of elemental ions after acid digestion. |
| Chloride Ion Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., dechlorinated or oxidized analogs) using gradient HPLC. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Specific Optical Rotation | [a]D Measurement | Measures rotation of plane-polarized light at 589 nm to confirm chiral integrity and concentration-dependent specific rotation. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of saturated aqueous suspension using calibrated glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser light. |
Technical Specifications of (R)-2-(1-aMinoethyl)-4-chlorophenol
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC), >=98.0% ee |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-2-(1-aMinoethyl)-4-chlorophenol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-2-(1-aMinoethyl)-4-chlorophenol
Safety Information of (R)-2-(1-aMinoethyl)-4-chlorophenol
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-2-(1-aMinoethyl)-4-chlorophenol
Industrial (R)-2-(1-aMinoethyl)-4-chlorophenol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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