China Factory Direct
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| CAS number | 122918-25-6 |
| Product name | 6-Bromo-2-pyridinecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key intermediate for constructing pyridine ring structures and participating in coupling reactions to prepare active pharmaceutical ingredients |
| Agrochemicals | Synthesis intermediate for insecticides | Applied in heterocyclic compound synthesis via functional group transformations of the cyano and bromo groups, supporting development of novel insecticides |
| Organic Synthesis | Raw material for specialty chemical synthesis | Employed in cross-coupling reactions—including Suzuki and Heck couplings—to prepare functionalized pyridine derivatives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., 2-bromo-6-methylpyridine, 2-chloro-6-cyanopyridine) using gradient HPLC-UV with a validated stability-indicating method. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., acetonitrile, dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis of toxic elements (Pb, Cd, Hg, As) after acid digestion, with detection limits compliant with ICH Q3D. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual non-volatile matter. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after sample dissolution and filtration. |
| Appearance (Color & Clarity) | Visual Inspection | Assessment of solution clarity and color (e.g., in methanol) against standardized references (e.g., APHA/Hazen scale) under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 °C using sodium D-line (589 nm) to confirm absence of chiral contamination (racemic compound expected). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.