China Factory Direct
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| CAS number | 123-08-0 |
| Product name | 4-Hydroxybenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical Industry | Synthesis of pharmaceutical intermediates | Used in the synthesis of anti-inflammatory drugs, antibiotics, and analgesics |
| Fine Fragrance Industry | Fragrance synthesis | Serves as a key intermediate in the synthesis of fragrance compounds such as vanillin |
| Pesticide Industry | Pesticide intermediates | Used in the synthesis of certain fungicides and herbicides |
| Dye Industry | Dye synthesis | Used in the synthesis of certain azo dyes and reactive dyes |
| Materials Science | Functional material preparation | Applied in the preparation of functional materials including liquid crystal materials and optoelectronic materials |
| Personal Care Industry | Preservative and fragrance ingredient | Incorporated into cosmetic preservative systems or fragrance formulations |
| Food Industry | Food additive | Used as a flavoring agent to enhance food aroma |
| Research Sector | Chemical reagent | Employed as an organic synthesis reagent in laboratory research |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Properties | Visual Inspection, Physical Property Measurement | Observe sample as white to off-white crystalline powder, determine melting point (literature value ~115–118°C), and check solubility (soluble in ethanol and ether, slightly soluble in water). |
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with methanol-water or acetonitrile-water as mobile phase. Use a UV detector at 254–280 nm to measure content, calculate by external standard method; effectively separates impurities. |
| Impurity Detection (e.g., Benzaldehyde, p-Hydroxybenzyl Alcohol, etc.) | HPLC or LC-MS | HPLC uses gradient elution to separate impurities, while LC-MS is used for structural identification. Detects trace organic impurities and degradation products, meeting ICH Q3B requirements. |
| Moisture Content | Karl Fischer Titration | Iodine and sulfur dioxide quantitatively react with water in pyridine and methanol. Water content is determined using potentiometric or coulometric methods with ppm-level accuracy. |
| Melting Point | Melting Point Apparatus | Determine melting range using capillary method or automatic melting point apparatus. A narrow melting range (~1–2°C) indicates high purity; abnormal melting points suggest impurities. |
| UV-Visible Absorption Spectrum | UV-Vis Spectrophotometry | Dissolve the sample in ethanol or methanol and measure characteristic absorption peak at 270–290 nm (λ_max ≈ 278 nm). Used for qualitative confirmation and quantitative analysis (requires calibration curve). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After ashing or digestion, use AAS to measure heavy metals such as lead, cadmium, and mercury. Meets pharmacopoeia limits (e.g., ≤10 ppm). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with DB-624 or similar capillary columns and FID detectors to detect residual solvents such as ethanol, acetone, and ethyl acetate, meeting ICH Q3C guidelines. |
| Inorganic Impurities (e.g., Chlorides, Sulfates, etc.) | Colorimetric Method or Ion Chromatography (IC) | Chlorides are measured by silver nitrate turbidity method; sulfates by barium chloride precipitation turbidity method. Ion chromatography provides more accurate results and can simultaneously detect multiple anions. |
| Crystallinity (Optional) | X-ray Powder Diffraction (XRPD) | Used to confirm crystal structure and crystallinity consistency, ensuring physical property stability across production batches. Particularly important for dissolution and stability in formulations. |
| Content Uniformity (In Formulations) | HPLC Method (For Active Pharmaceutical Ingredients in Formulations) | If used as active ingredient in formulations, measure p-hydroxybenzaldehyde content in multiple formulation units according to pharmacopoeia requirements. Assess uniformity (RSD ≤5%). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC) |
| Melting Point | 115-117°C |
| Total Impurities | <=1.5% (GC) |
| Single Impurity | <=0.5% (GC) |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.