4-CHLORO-L-PHENYLALANINE HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 123053-23-6 |
| Product name | 4-CHLORO-L-PHENYLALANINE HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-CHLORO-L-PHENYLALANINE HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLORO-L-PHENYLALANINE HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLORO-L-PHENYLALANINE HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthesis intermediate for preparing drug molecules containing phenylalanine motifs | Chlorophenylalanine moiety introduced via asymmetric synthesis or enzymatic catalysis, incorporated into peptide or small-molecule drug construction |
| Biochemical Research | Amino acid analog used to study protein translation, enzyme inhibition, or metabolic pathway disruption | Substitutes for natural phenylalanine in cell-free translation systems or cell culture to assess biological effects |
| Medicinal Chemistry | Precursor for synthesizing antimicrobial, antitumor, or neuroactive compounds | Target derivatives generated via amidation, esterification, or coupling reactions for structure–activity relationship (SAR) studies |
| Peptide Synthesis | Used in solid-phase or solution-phase synthesis of custom peptides containing non-natural amino acids | 4-Chloro-L-phenylalanine residue incorporated at specific positions in the peptide chain using Fmoc/t-Boc strategies |
Manufacturing Quality Control of 4-CHLORO-L-PHENYLALANINE HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving L- and D-enantiomers. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile content including residual solvents and moisture. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration | Determination of chloride ion concentration using silver nitrate titrant and a silver/silver chloride indicator electrode. |
| pH (1% w/v aqueous solution) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Quantification of chiral compound’s ability to rotate plane-polarized light at specified wavelength (e.g., 589 nm) and concentration. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., des-chloro analog, diastereomers) using gradient HPLC with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of total water content based on iodine-sulfur dioxide reaction stoichiometry. |
| Residue on Ignition | Gravimetric (500-600 C) | Mass of non-volatile inorganic residue remaining after high-temperature ashing, indicating inorganic salt impurities. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
Technical Specifications of 4-CHLORO-L-PHENYLALANINE HCL
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 220–224 °C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | -22.0 to -26.0 ° (c=1, 6N HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-CHLORO-L-PHENYLALANINE HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 4-CHLORO-L-PHENYLALANINE HCL
Industrial 4-CHLORO-L-PHENYLALANINE HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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