D-Proline, 2-methyl-, hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 123053-48-5 |
| Product name | D-Proline, 2-methyl-, hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Proline, 2-methyl-, hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Proline, 2-methyl-, hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Proline, 2-methyl-, hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral auxiliary or intermediate in drug synthesis, e.g., for preparing antidepressants | Reacted with target compounds to form diastereomeric mixtures, followed by isolation of the desired chiral product via crystallization or other separation methods |
| Chemicals | Used as a chiral building block in organic synthesis | Typically involves asymmetric synthesis techniques, including but not limited to asymmetric reduction, oxidation, and cycloaddition reactions |
| Research | Used as a precursor to chiral catalysts or ligands | Chemically modified to generate chiral catalysts or ligands with specific catalytic activity for enabling various asymmetric transformations |
Manufacturing Quality Control of D-Proline, 2-methyl-, hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after drying sample at 105 C for 2 hours under controlled humidity and airflow. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, using inductively coupled plasma optical emission spectroscopy with matrix-matched calibration. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint determined by potential inflection. |
| pH of Aqueous Solution | pH Potentiometry | Measurement of pH in a 1% w/v aqueous solution using a calibrated glass electrode system. |
| Specific Optical Rotation | [alpha]D | Measurement of rotation angle of plane-polarized light at 589 nm using a digital polarimeter, corrected for concentration and path length. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid transition occurs, using calibrated capillary apparatus per USP <741>. |
| Related Substances | HPLC-UV | Detection and quantification of impurities using gradient reverse-phase HPLC with UV detection at multiple wavelengths (210 and 254 nm). |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent; water reacts stoichiometrically with iodine, sulfur dioxide, and base in methanol medium. |
| Appearance | Visual Inspection | Assessment of color and physical state (white to off-white crystalline powder) against standard reference under controlled lighting and white background. |
Technical Specifications of D-Proline, 2-methyl-, hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +37.0 to +40.0 deg (c=1, in 1M HCl) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 168 to 172 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Proline, 2-methyl-, hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Proline, 2-methyl-, hydrochloride
Safety Information of D-Proline, 2-methyl-, hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-Proline, 2-methyl-, hydrochloride
Industrial D-Proline, 2-methyl-, hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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