8-Bromo-1-chloroisoquinoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1233025-78-9 |
| Product name | 8-Bromo-1-chloroisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 8-Bromo-1-chloroisoquinoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-Bromo-1-chloroisoquinoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-Bromo-1-chloroisoquinoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a bifunctional building block; the differential reactivity of the chloro and bromo groups enables sequential nucleophilic substitution or cross-coupling reactions to construct drug molecule scaffolds. |
| Organic Synthesis | Organic Synthesis Building Block | Enables selective coupling of diverse functional groups via cross-coupling reactions such as Suzuki and Buchwald–Hartwig to construct isoquinoline derivatives. |
| Materials Chemistry | Functional Material Intermediate | Used in the synthesis of organic molecules with tailored optoelectronic properties, serving as a precursor for OLED materials or organic semiconductor materials. |
| Research & Development | Structural Modification Reagent | Applied at laboratory scale for functionalization of the isoquinoline ring system to explore novel reaction pathways and bioactive molecules. |
Manufacturing Quality Control of 8-Bromo-1-chloroisoquinoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at characteristic wavelength. |
| Related Substances | HPLC-UV | Separates and detects impurities based on retention time and UV response relative to main peak. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents by gas chromatographic separation and flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-OES | Detects trace metal contaminants by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Bromide Content | Ion Chromatography | Separates and quantifies bromide ions using anion-exchange column and conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid under controlled heating. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in intensity of scattered laser light. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension using calibrated glass electrode. |
Technical Specifications of 8-Bromo-1-chloroisoquinoline
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 8-Bromo-1-chloroisoquinoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 8-Bromo-1-chloroisoquinoline
Industrial 8-Bromo-1-chloroisoquinoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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