1-Hydroxybenzotriazole hydrate Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 123333-53-9 |
| Product name | 1-Hydroxybenzotriazole hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-Hydroxybenzotriazole hydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Hydroxybenzotriazole hydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Hydroxybenzotriazole hydrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Racemization inhibitor and coupling promoter in peptide synthesis | Used in solid-phase peptide synthesis (SPPS) in conjunction with carbodiimide reagents (e.g., EDC) to enhance amide bond formation efficiency and minimize racemization |
| Biochemistry | Chemical modification reagent for proteins and peptides | Activates carboxyl groups to facilitate stable amide bond formation with amino groups |
| Organic Synthesis | Carboxylic acid activating reagent | Combined with condensing agents such as DCC or EDC for condensation reactions including esterification and amidation |
| Materials Science | Auxiliary reagent for functional polymer synthesis | Facilitates amide bond formation between monomers during polymerization to produce functional polyamide materials |
Manufacturing Quality Control of 1-Hydroxybenzotriazole hydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 220-254 nm, relative to a certified reference standard. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 750-800 C to constant weight and measuring inorganic residue as percentage of original mass. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, using plasma emission spectroscopy calibrated with heavy metal standards. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous extract using anion-exchange column. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Precipitation of sulfate as BaSO4 in acidic medium; turbidity measured spectrophotometrically at 420 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC with diode-array detection and comparison to reference standards or threshold limits. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as temperature range where solid transforms to liquid. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in 1% w/v aqueous suspension using calibrated pH electrode. |
| Appearance | Visual Inspection | Assessment under controlled white light against specified criteria for color, clarity, and absence of visible particulates. |
| Solubility in Water | Qualitative Solubility Test | Observation of complete dissolution of specified amount (e.g., 1 g) in defined volume of water at 20 C with gentle agitation. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Mass loss measured upon heating at 105 C for 2 h, reported as percentage of initial mass. |
Technical Specifications of 1-Hydroxybenzotriazole hydrate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 103–107°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-Hydroxybenzotriazole hydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Hydroxybenzotriazole hydrate
Safety Information of 1-Hydroxybenzotriazole hydrate
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-Hydroxybenzotriazole hydrate
Industrial 1-Hydroxybenzotriazole hydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply