2,4-DIFLUORO-5-NITROANILINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 123344-02-5 |
| Product name | 2,4-DIFLUORO-5-NITROANILINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-DIFLUORO-5-NITROANILINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-DIFLUORO-5-NITROANILINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-DIFLUORO-5-NITROANILINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of fluorinated pesticide intermediates | Used as a key intermediate in nitro reduction, coupling, and fluorination reactions to produce high-efficacy insecticides and fungicides such as flutolanil and fipronil |
| Pharmaceuticals | Synthesis of antiviral and antitumor drug intermediates | Applied in nucleophilic substitution, reductive amination, or coupling reactions to construct fluorinated aniline structural units for developing HIV protease inhibitors or kinase inhibitors |
| Dyes and Pigments | Synthesis of high-performance fluorinated azo dyes | Used as a diazo component in coupling reactions with coupling components to produce deep-tone dyes exhibiting high lightfastness and weather resistance |
| Polymers | Synthesis of fluorinated functional monomers | Introduced into polymer chains via diazotization, enabling the production of heat-resistant and chemically resistant fluorinated polymers or copolymers |
Manufacturing Quality Control of 2,4-DIFLUORO-5-NITROANILINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., isomers, reduction/by-product derivatives) using gradient HPLC/UPLC with UV or mass-selective detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization or mass spectrometric detection to quantify residual solvents (e.g., methanol, DMF, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS or AAS | Quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion, based on USP <232>/<233> or ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration using iodine generation to determine trace water content in accordance with ASTM E203 or USP <921>. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating of a capillary sample; used for identity and purity assessment per Ph. Eur. 2.2.14. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration for chloride ions derived from synthesis residues. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic ash content after high-temperature incineration at 600–800 °C per USP <281>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder using light scattering principles to determine D10, D50, D90 values per ISO 13320. |
| Bulk and Tapped Density | ASTM D6393 (Carr Index) | Mechanical tapping of a known powder mass in a graduated cylinder to determine density parameters relevant to flowability and processability. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of surface proton activity in a standardized aqueous slurry to assess acidic/basic impurity influence. |
| Organic Volatile Impurities (e.g., Nitrobenzene, Aniline Derivatives) | GC-MS | Targeted screening and quantification of genotoxic or volatile organic impurities using selective ion monitoring after headspace or direct injection. |
| Specific Optical Rotation | Polarimetry | Measurement of chiral rotation (though compound is achiral, used to confirm absence of chiral contaminants or racemization artifacts). |
Technical Specifications of 2,4-DIFLUORO-5-NITROANILINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-DIFLUORO-5-NITROANILINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-DIFLUORO-5-NITROANILINE
Packaging of 2,4-DIFLUORO-5-NITROANILINE
Industrial 2,4-DIFLUORO-5-NITROANILINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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