4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 123654-26-2 |
| Product name | 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidepressant vilazodone | Prepared via multistep organic synthesis, including nitration, reduction, cyclization, and carboxyl group introduction |
| Chemical R&D | Used to construct heterocyclic compound libraries containing the benzofuran scaffold | Serves as a starting material in Suzuki coupling, amidation, alkylation, and other reactions for medicinal chemistry or structure–activity relationship (SAR) studies |
Manufacturing Quality Control of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white or off-white crystalline powder), and presence of foreign particles with the naked eye to determine compliance with quality standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Measure the sample's infrared absorption spectrum and compare it with the reference standard spectrum to confirm characteristic functional groups; HPLC: Under specified chromatographic conditions, compare the retention time of the main peak of the test sample with that of the reference standard. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., methanol-water or acetonitrile-buffer salt mixture); detect using a UV detector (typically at 220–260 nm wavelength); calculate the content of the main component by external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main component from potential impurities (e.g., synthetic intermediates, degradation products) using gradient or isocratic elution; quantify using area normalization or the main-component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with polar or non-polar capillary columns and a flame ionization detector (FID); detect residual solvents such as methanol, ethanol, dichloromethane, and ethyl acetate according to pharmacopoeial methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Atmospheric Pressure Constant-Temperature Drying | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and calculate the percentage weight loss to assess the content of water and volatile substances. |
| Residue on Ignition | High-Temperature Ignition | Incinerate the sample at high temperature (typically 700–800°C) and weigh the residual inorganic material to control the total amount of inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, determine the content of heavy metal elements such as lead, cadmium, mercury, and arsenic using AAS or ICP-MS to ensure compliance with specified limits. |
| pH Value (if prepared as a solution) | pH Meter Method | Dissolve the sample in water at a specified concentration (e.g., 1%) and measure the pH value using a calibrated pH meter to assess whether acidity or alkalinity meets the standard. |
Technical Specifications of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
Safety Information of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid
Industrial 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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