China Factory Direct
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| CAS number | 123843-67-4 |
| Product name | 4-Bromo-2,6-difluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing fluorinated herbicides and insecticides | Introduces cyano and halogen groups via nucleophilic substitution or coupling reactions to construct fluorinated aromatic ring structures |
| Pharmaceuticals | Intermediate for synthesizing anticancer, antiviral, or central nervous system drugs | Used as a benzonitrile derivative in transition metal-catalyzed reactions, including Suzuki coupling and Buchwald-Hartwig amination |
| Materials Science | Monomer for synthesizing high-performance polymers or liquid crystal materials | Incorporates fluorinated nitrile groups via polymerization or copolymerization to enhance thermal stability and dielectric properties |
| Organic Synthesis | Fluorinated aromatic nitrile reagent for constructing complex molecular frameworks | Serves as a functional group transformation precursor in multistep syntheses, e.g., hydrolysis to carboxylic acids or reduction to amines |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Main Component Content) | HPLC (High-Performance Liquid Chromatography) | Using a reverse-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (typically at 220–254 nm wavelength), the content of 4-bromo-2,6-difluorobenzonitrile is calculated by area normalization or external standard method. |
| Related Substances (Impurities) | HPLC (High-Performance Liquid Chromatography) | Under the same conditions as purity testing, this method separates and quantifies potential organic impurities (such as starting materials, intermediates, by-products, etc.). The level of impurities is assessed by comparing the peak areas of each impurity to that of the main component. |
| Residual Solvents | GC (Gas Chromatography) | Using headspace or direct injection, with polar or non-polar capillary columns and an FID detector, this method identifies and quantifies residual organic solvents (such as toluene, dichloromethane, DMF, etc.) from the production process. |
| Moisture | Karl Fischer Titration | This method uses a Karl Fischer reagent to react quantitatively with water in the sample. The moisture content is determined by coulometric or volumetric methods, suitable for trace moisture analysis. |
| Melting Point | Capillary Melting Point Determination | The sample is placed in a melting point capillary tube and heated at a controlled rate. The temperature range from initial melting to complete melting is observed to assess the purity and consistency of the compound. |
| Appearance/Physical Form | Visual Inspection | The sample is visually examined under standard lighting conditions for color, physical state (e.g., white to off-white crystalline powder), and presence of visible foreign matter. |
| Heavy Metals | AAS (Atomic Absorption Spectroscopy) or ICP-MS (Inductively Coupled Plasma Mass Spectrometry) | After acid digestion of the sample, AAS or ICP-MS is used to determine the residual levels of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeia or relevant regulatory limits. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.