China Factory Direct
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| CAS number | 123853-39-4 |
| Product name | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key pharmaceutical intermediate for the antihypertensive drug clevidipine | Used in the chemical synthesis of clevidipine, primarily participating in esterification to construct the dihydropyridine ring structure |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~235 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD or UPLC-MS | Separation and identification of impurities using gradient HPLC with diode-array or mass spectrometric detection; quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., acetone, methanol, ethyl acetate) against calibrated standards. |
| Heavy Metals (Total) | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on isotopic mass detection with ultra-trace sensitivity. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Titration with standardized silver nitrate solution using a silver indicator electrode; endpoint detected by potential inflection due to AgCl precipitation. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical generation of iodine in anhydrous medium; water content determined from total charge required to maintain stoichiometric iodine concentration. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700–800 °C followed by weighing of non-volatile inorganic residue; measures inorganic ash content. |
| Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution using a digital polarimeter; confirms chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine volumetric particle size distribution in dry or suspended state. |
| pH (1% w/v aqueous suspension) | pH Potentiometry | Measurement using calibrated glass electrode in a standardized aqueous suspension; assesses surface acidity/basicity and hydrolytic stability. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.