N-Boc-4-piperidinemethanol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 123855-51-6 |
| Product name | N-Boc-4-piperidinemethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-4-piperidinemethanol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-4-piperidinemethanol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-4-piperidinemethanol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of various drug molecules, including opioid receptor antagonists, antidepressants, and antipsychotics | Employed in organic synthesis to construct piperidine-containing active pharmaceutical ingredients (APIs) via deprotection (e.g., Boc removal), oxidation, or substitution reactions |
| Agrochemicals | Used to synthesize biologically active pesticides or plant growth regulators | Serves as a nitrogen-containing heterocyclic building block in multi-step syntheses, introducing the piperidinemethanol moiety to enhance molecular target selectivity or stability |
| Chemical R&D | Used as a versatile synthon for constructing libraries of complex nitrogen-containing heterocyclic compounds | Enables selective functional group transformations via Boc-protecting group strategies, commonly applied in combinatorial chemistry and high-throughput screening platforms |
Manufacturing Quality Control of N-Boc-4-piperidinemethanol
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observed visually for color, physical state (e.g., white to off-white crystalline or powder), and presence of foreign particles. |
| Identification | Infrared Spectroscopy (IR) Nuclear Magnetic Resonance Hydrogen Spectroscopy (¹H NMR) |
IR: Compare characteristic functional group absorption peaks (e.g., Boc group ~1700 cm⁻¹, hydroxyl group ~3400 cm⁻¹); ¹H NMR: Confirm characteristic proton chemical shifts (e.g., piperidine ring protons, CH₂OH, tert-butyl groups). |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with appropriate mobile phase (e.g., acetonitrile-water or methanol-water system, often containing buffer salts or acid to adjust pH). Quantify the main component using external standard method or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same or optimized conditions as content determination; separate and quantify potential impurities (e.g., de-Boc product, oxidation products, residual starting materials). Gradient elution is typically used to improve resolution. |
| Water Content | Karl Fischer Titration | Utilizes the quantitative reaction between iodine and sulfur dioxide in the presence of pyridine/imidazole with water. Accurately measures moisture content, suitable for moisture-sensitive organic compounds. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns to detect possible residual organic solvents from synthesis or purification processes (e.g., dichloromethane, methanol, ethyl acetate). |
| Melting Point | Melting Point Apparatus | Determine the temperature range at which the sample transitions from solid to liquid, used to assess purity (pure substances have narrow melting ranges; impurities lower and broaden the melting range). |
| Specific Rotation (if chiral) | Polarimeter | If N-Boc-4-piperidinemethanol is an optically active form (e.g., specific enantiomer), measure its specific rotation to confirm optical purity. |
| pH (in Solution) | pH Meter | Dissolve the sample in a specified concentration of aqueous solution or appropriate solvent system, then measure pH to indirectly reflect the presence of acidic or basic impurities. |
| Residue on Ignition / Ash Content | High-Temperature Incineration Method | Ignite the sample at high temperature (typically 700–800°C) and determine the weight of inorganic residue, used to control inorganic impurities. |
Technical Specifications of N-Boc-4-piperidinemethanol
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -5.0° to +5.0° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-4-piperidinemethanol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-4-piperidinemethanol
Packaging of N-Boc-4-piperidinemethanol
Industrial N-Boc-4-piperidinemethanol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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