China Factory Direct
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| CAS number | 124072-61-3 |
| Product name | 3-(Methylamino)propanoic acid, N-BOC protected |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Peptide drug synthesis | Used as a non-natural amino acid derivative containing a carboxylic acid group in solid-phase or solution-phase peptide synthesis to construct N-methylated peptide backbones. |
| Pharmaceuticals | Drug building block | Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) containing the N-methylglycine structural motif. |
| Biochemistry | Peptide structure modification | Applied to introduce N-methyl groups, thereby improving metabolic stability, membrane permeability, or modulating conformation of peptide therapeutics. |
| Organic synthesis | Protecting group chemistry | Leverages the acid-labile nature of the Boc group for amine protection and functional group transformations during the synthesis of complex organic molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, toluene) by headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated electrochemically in a methanol-based reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using a digital polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Residual Metals (Na, K, Fe, Cu, Ni) | ICP-OES | Quantifies trace metals after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects ultra-trace heavy metals post-microwave digestion via mass spectrometric detection of elemental isotopes. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation of meniscus movement. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified vacuum and temperature conditions to assess volatile content. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in a standardized suspension or solution using a calibrated glass electrode. |
| Residual Boc Protecting Group | HPLC-UV or TLC | Confirms complete deprotection or absence of Boc-related impurities via retention time comparison (HPLC) or Rf value (TLC). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.