China Factory Direct
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| CAS number | 124289-21-0 |
| Product name | 3-BROMO-5-METHYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., analogues of BTK inhibitors) | Brominated aryl nitriles participate in Suzuki coupling, cyanide hydrolysis, or reduction to construct targeted molecular scaffolds |
| Agrochemical Intermediates | Aromatic heterocyclic precursor for synthesizing novel insecticides and fungicides | Cyano group conversion introduces pharmacophores such as amides and tetrazoles; bromine atom provides a site for further functionalization |
| Organic Synthesis | Multifunctional building block for preparing poly-substituted arenes containing bromo, cyano, and methyl groups | Typical processes include Pd-catalyzed cross-coupling (e.g., Heck, Stille), nucleophilic substitution, and cyano derivatization (e.g., reaction with sodium azide to form tetrazoles) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and gradient elution; detection at 220 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling and FID | Headspace equilibration followed by GC separation to quantify volatile organic solvents (e.g., methanol, acetone, toluene). |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in argon plasma; quantification via element-specific emission wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column and detection via suppressed conductivity. |
| Residue on Ignition | Gravimetric analysis after high-temperature ashing | Sample ignited at 700-800 C to remove organic matter; residual inorganic ash weighed as sulfate-free residue. |
| Melting Point | Capillary melting point apparatus | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid. |
| Appearance | Visual inspection against standard white background | Assessment of physical state, color, and presence of visible particulates or discoloration under controlled lighting. |
| Bulk Density | Tap density measurement (ASTM D1895) | Mass per unit volume of powder after standardized tapping; measured using calibrated graduated cylinder and mechanical tap device. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Analysis of scattered laser light intensity patterns to calculate particle size distribution based on Mie theory. |
| pH of Aqueous Suspension | pH meter measurement | Electrochemical measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) at 25 C. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.