2-Bromo-6-methoxybenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1245647-50-0 |
| Product name | 2-Bromo-6-methoxybenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-6-methoxybenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-6-methoxybenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-6-methoxybenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of biologically active drug molecules, such as kinase inhibitors or antitumor compounds | Serves as an aryl nitrile building block in Suzuki coupling, nucleophilic substitution, or cyclization reactions to construct complex heterocyclic frameworks |
| Agrochemical Intermediates | Acts as a lead structure for synthesizing novel, high-efficacy insecticides or herbicides | Enables introduction of specific substituents via cyano group transformations (e.g., hydrolysis, reduction) or functionalization of the bromo group |
| Organic Synthesis Reagents | Used to build functional molecules or ligands containing a methoxybenzonitrile structure | Undergoes metal-catalyzed cross-coupling reactions (e.g., Heck, Sonogashira) at the bromo site, or participates in multicomponent condensation reactions via the nitrile group |
Manufacturing Quality Control of 2-Bromo-6-methoxybenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., 2-bromo-6-hydroxybenzonitrile, des-methoxy analogs) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS or ICP-OES | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission or mass spectrometric detection. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Anion exchange chromatography with conductivity detection, or argentometric titration using silver nitrate for quantification of chloride ions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (ASTM D1565). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting (white background, daylight-equivalent illumination). |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700–800 °C) to determine inorganic ash content (USP <281>). |
Technical Specifications of 2-Bromo-6-methoxybenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-6-methoxybenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-6-methoxybenzonitrile
Safety Information of 2-Bromo-6-methoxybenzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Bromo-6-methoxybenzonitrile
Industrial 2-Bromo-6-methoxybenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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