(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 124655-09-0 |
| Product name | (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 124655-09-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 124655-09-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 124655-09-0
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for active pharmaceutical ingredients (APIs) | Used as a chiral building block in the asymmetric synthesis of the antidiabetic drug sitagliptin |
| Chemical Synthesis | Chiral auxiliary | Applied as a chiral inducer in asymmetric catalytic reactions to achieve high enantioselectivity |
| Pharmaceutical R&D | Intermediate for antiviral agents | Employed in stereoselective synthesis steps of certain antiviral compounds |
| Fine Chemicals | Organic synthesis reagent | Used to construct 1,3-dioxane moieties in complex molecules, serving as either a protecting group or a structural motif |
Manufacturing Quality Control of 124655-09-0
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white solid, colorless oily liquid), and the presence of visible foreign matter. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically 210–254 nm) to determine main peak purity via external standard or area normalization methods. |
| Chiral Purity (Enantiomeric Excess) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employ a chiral stationary phase column to separate enantiomers and assess the level of (4R-cis) enantiomeric impurities. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, ethyl acetate) in accordance with ICH guidelines. |
| Moisture Content | Karl Fischer Titration | Measure total water content (free and bound water) to ensure compliance with loss on drying requirements. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range for solid samples to assist in assessing compound purity and consistency. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze compound structure using ¹H-NMR and ¹³C-NMR to confirm molecular framework and substituent positions. |
| Structural Confirmation | Mass Spectrometry (MS, e.g., LC-MS or EI-MS) | Identify molecular ion peaks ([M+H]+ or M•+) to verify molecular weight and consistency with the target structure. |
| Assay | HPLC External Standard Method | Establish a calibration curve using a reference standard of known concentration to quantitatively determine the content of the target compound in the sample. |
| Related Substances (Impurity Profiling) | HPLC-DAD or LC-MS | Analyze process-related impurities and degradation products, identifying and quantifying individual impurity peaks; typically, individual impurities should be ≤0.5%. |
Technical Specifications of 124655-09-0
| Test Item | Specification |
|---|---|
| Appearance | Yellow sticky liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -5.0 to -3.0 deg (c=1, CHCl3) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 124655-09-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 124655-09-0
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Industrial 124655-09-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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