China Factory Direct
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| CAS number | 125-46-2 |
| Product name | USNIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Applications | Processing |
|---|---|---|
| Pharmaceuticals | Antibiotics and antiseptics (for treating skin infections, wounds, burns, and tinea) | Acidic alcohol extraction followed by purification and formulation into ointments, powders, or solutions |
| Cosmetics | Preservative, anti-acne agent, and deodorant (for skincare products, toothpaste, and deodorants) | Dissolved in ethanol or propylene glycol and incorporated into the formulation system |
| Agriculture | Plant growth regulator and fungicide (for controlling crop mold) | Formulated as emulsions or aqueous solutions for spraying |
| Food | Natural preservative (for extending food shelf life) | Incorporated into food packaging materials or added directly within regulatory limits |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | A C18 reversed-phase column is used with a mobile phase of methanol-water or acetonitrile-water under gradient elution. Detection is performed at 245–290 nm using a UV detector for quantitative analysis of usnic acid. This method offers high sensitivity and good reproducibility, suitable for the quantitative analysis of usnic acid in raw materials and formulations. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Usnic acid shows characteristic absorption peaks near 230 nm and 288 nm. Preliminary identification is achieved by comparing the UV spectra of the sample with that of a reference standard. Simple to operate, this method is commonly used for rapid qualitative screening. |
| Purity Test | Thin-Layer Chromatography (TLC) | Silica gel G plates are used with a developing solvent such as toluene-ethyl acetate-formic acid (e.g., 15:5:1). After development, spots are observed under UV light (254/365 nm), or visualized using a spray reagent (e.g., 10% sulfuric acid in ethanol) followed by heating. Purity and impurities are assessed based on Rf values and spot colors. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Infrared scanning of the sample reveals characteristic absorption peaks of usnic acid at 1670–1700 cm⁻¹ (carbonyl stretching vibration) and 1600 cm⁻¹ (aromatic ring skeleton vibration), used to confirm functional groups and molecular structure. |
| Assay and Multi-component Analysis | Ultra-Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS) | Combines the high separation efficiency of UPLC with the high sensitivity of mass spectrometry, enabling simultaneous determination of usnic acid, its isomers, and metabolites. Suitable for trace analysis and structural identification in complex matrices. |
| Moisture Content | Karl Fischer Titration | Determines water content based on the quantitative reaction of iodine and sulfur dioxide with water in an anhydrous environment. Ensures the moisture level of usnic acid raw material meets quality specifications. |
| Heavy Metals and Residual Solvents | Gas Chromatography (GC) or Atomic Absorption Spectroscopy (AAS) | GC is used to detect residual solvents such as ethanol and methanol; AAS or ICP-MS is employed to measure heavy metal residues (e.g., lead, cadmium, arsenic), ensuring compliance with pharmaceutical safety limits. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15° to -25° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.