FMOC-DAB(BOC)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 125238-99-5 |
| Product name | FMOC-DAB(BOC)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-DAB(BOC)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-DAB(BOC)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-DAB(BOC)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protected amino acid monomers for solid-phase peptide synthesis | Used as a doubly orthogonally protected derivative of L-2,4-diaminobutyric acid to selectively construct therapeutic peptides containing vicinal diamine motifs (e.g., antimicrobial peptides, targeted conjugates); Fmoc group removed with piperidine, Boc group removed with TFA, enabling stepwise coupling and deprotection |
| Biochemical Research | Building block for synthesizing protein/peptide structure–function probes | Applied to introduce a site-specifically modifiable primary amine side chain (γ-amino group retained as Boc-protected; α-amino group deprotected via Fmoc removal prior to coupling with fluorescent labels, biotin, or crosslinkers), supporting structure–activity relationship studies and chemical biology tool development |
Manufacturing Quality Control of FMOC-DAB(BOC)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260–280 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., Chirobiotic T or Lux Cellulose-2), with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of residual solvents (e.g., DMF, DCM, EtOAc) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Chloride | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV (Forced Degradation Compatible) | Detection and quantification of process-related impurities and degradation products using gradient HPLC-UV under stressed conditions (acid/base/oxidative/thermal). |
| Loss on Drying (LOD) | Gravimetric Analysis (105 °C, 2 h) | Mass loss measurement upon drying under controlled temperature and vacuum to determine volatile and moisture content. |
| Optical Rotation | [α]D Measurement (Polarimetry) | Specific rotation determination at 589 nm (Na-D line) in specified solvent (e.g., 1 M HCl) to confirm stereochemical integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory following dispersion in air. |
| Microbial Contamination | Membrane Filtration (USP <61>) | Enumeration of aerobic microorganisms via filtration, membrane transfer to culture media, and colony counting after incubation. |
| pH (1% w/v aqueous suspension) | pH Potentiometry | Measurement of hydrogen ion activity in a standardized aqueous suspension using a calibrated pH electrode. |
| Residual Fmoc/TBoc Protecting Groups | HPLC-UV or LC-MS | Specific detection and quantification of unreacted or cleaved protecting group fragments (e.g., dibenzofulvene, tert-butanol derivatives) using retention time and spectral matching. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (e.g., 1 °C/min) per USP <741>. |
Technical Specifications of FMOC-DAB(BOC)-OH
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -15.5 to -13.5 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-DAB(BOC)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-DAB(BOC)-OH
Packaging of FMOC-DAB(BOC)-OH
Industrial FMOC-DAB(BOC)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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