China Factory Direct
|
|
| CAS number | 125328-80-5 |
| Product name | N-(4-BROMO-3-CHLORO-2-METHYL-PHENYL) ACETAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of anti-inflammatory, antimicrobial, or antitumor active compounds | Employed as an aromatic amine building block in acylation, coupling, or cyclization reactions to construct complex molecular frameworks |
| Agrochemical Intermediates | Used in the synthesis of insecticides or herbicides containing bromo- and chloro-substituted phenyl groups | Functionalized via nucleophilic substitution or metal-catalyzed coupling to enhance biological activity |
| Organic Synthesis | Served as a versatile aromatic building block for constructing heterocycles or functional materials | Subjected to Suzuki, Heck, and other cross-coupling reactions via the bromine atom; the chlorine atom allows for selective activation and derivatization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., starting materials, dehalogenated by-products, acetylation side-products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., dichloromethane, ethyl acetate, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, based on elemental emission or mass spectral signals. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions (e.g., from hydrolytic degradation) via IC conductivity detection, or direct titration with AgNO₃ using potentiometric endpoint detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 700–800 °C after sulfuric acid treatment; residue weight reflects inorganic impurities. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, indicating crystallinity and identity/purity. |
| Appearance & Color | Visual Inspection / Hazen/APHA Color Scale | Subjective visual assessment against water or platinum-cobalt standards to detect discoloration or particulates. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values, relevant for handling and formulation performance. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm chiral integrity (though compound is achiral, used to detect chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-purple solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.