China Factory Direct
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| CAS number | 125353-44-8 |
| Product name | (S)-1,1,1-TRIFLUOROISOPROPYLAMINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates for synthesizing chiral amine active pharmaceutical ingredients (APIs) containing a trifluoromethyl group, such as antidepressants and antivirals | Used as a chiral building block in coupling reactions, reductive amination, or protection/deprotection sequences—commonly applied to construct the (S)-configured trifluoroisopropylamine side chain |
| Agrochemicals | Key structural motif in novel chiral herbicides and insecticides | Applied in synthesizing enantioselective heterocyclic compounds bearing a trifluoroisopropylamino group (e.g., triazolinone derivatives), with target stereochemistry introduced via asymmetric synthesis or chiral resolution |
| Materials Science | Monomer precursor for specialty fluorinated functional materials | Converted into trifluoroisopropylamino-containing fluorescent dyes, liquid crystal molecules, or organic semiconductor intermediates via acylation, sulfonylation, or condensation with aldehydes/ketones |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Water Content | Karl Fischer titration | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol-based medium. |
| Residual Solvents | Gas Chromatography (GC) with FID | Separation and quantification of volatile organic solvents using capillary column and flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element detection of trace metal impurities by plasma ionization and mass spectrometric analysis. |
| Chloride Ion | Ion Chromatography (IC) | Anion separation on ion-exchange column with suppressed conductivity detection for quantitative chloride determination. |
| Related Substances | HPLC with UV detection | Detection and quantification of structurally related impurities using gradient elution and UV absorbance. |
| Residue on Ignition | Gravimetric analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| pH of Aqueous Solution | Potentiometric pH measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Melting Point | Capillary melting point apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| Bulk Density | Tap density measurement | Volume reduction of a powder sample after standardized mechanical tapping; calculated as mass per tapped volume. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (by NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | +24.0 to +26.0° (c=1, in MeOH) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.