2-Fluoro-6-hydroxyphenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1256345-60-4 |
| Product name | 2-Fluoro-6-hydroxyphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-6-hydroxyphenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-6-hydroxyphenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-6-hydroxyphenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing fluorinated benzimidazole-based anticancer drugs | Employed in Suzuki coupling reactions to construct C–C bonds with haloarenes under palladium catalysis |
| Agrochemicals | Introduces fluorinated phenylboronic acid structural units into novel fluorinated insecticides | Participates in cross-coupling reactions via the boronic acid group to modify the active molecular scaffold |
| Materials Science | Building block for fluorinated organic light-emitting diode (OLED) hole-transport materials | Used as a boronic acid-functionalized monomer, incorporated into conjugated polymer backbones via condensation or coupling reactions |
Manufacturing Quality Control of 2-Fluoro-6-hydroxyphenylboronic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, physical state (e.g., white to off-white crystalline powder), presence of foreign matter or agglomeration, etc. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm molecular structure based on characteristic absorption peaks in infrared spectrum (e.g., B–OH, C–F, O–H, aromatic ring skeletal vibrations). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Determine hydrogen spectrum in deuterated solvent; compare with characteristic chemical shifts (e.g., aromatic protons, hydroxyl groups, boronic acid protons). | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase C18 column with UV detector (typically 220–280 nm); quantify using external standard method or area normalization. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same conditions as content determination or gradient elution program; separate and quantify potential impurities (e.g., defluorinated products, oxidized products). |
| Water Content | Karl Fischer Titration | Determine moisture content via potentiometric or coulometric Karl Fischer titration, suitable for water-sensitive boronic acid compounds. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection to detect organic solvents (e.g., methanol, ethanol) potentially residual from synthesis or purification processes. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range as an auxiliary indicator of purity and identity. |
| pH (Solution) | pH Meter Measurement | Prepare a solution at a specified concentration (e.g., 1% w/v), then measure pH to evaluate acidity/basicity and boric acid dissociation behavior. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) or Titration Method | Determine total boron content via ICP-OES, or indirectly measure boric acid content using mannitol complexation followed by acid-base titration. |
| Heavy Metals | ICP-MS or Atomic Absorption Spectroscopy (AAS) | Detect residual heavy metals such as lead, arsenic, cadmium, and mercury, complying with pharmacopoeial or ICH Q3D guidelines. |
Technical Specifications of 2-Fluoro-6-hydroxyphenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145–149 °C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-6-hydroxyphenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-6-hydroxyphenylboronic acid
Safety Information of 2-Fluoro-6-hydroxyphenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Fluoro-6-hydroxyphenylboronic acid
Industrial 2-Fluoro-6-hydroxyphenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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