China Factory Direct
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| CAS number | 125700-67-6 |
| Product name | 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Industry | Condensing agent for peptide bond formation | Used in solid-phase peptide synthesis (SPPS) for amino acid coupling; activates carboxyl groups to generate active ester intermediates |
| Organic Synthesis | Condensing agent for amide, ester, and heterocyclic compound synthesis | Facilitates dehydration condensation by reacting with carboxylic acids and amines/alcohols in inert solvents (e.g., DMF, DCM) |
| Biochemical Research | Reagent for protein modification and labeling | Enables covalent modification of biomolecules containing amino or carboxyl groups under mild conditions |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (typically white to off-white crystalline powder) to determine compliance with standard requirements. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with acetonitrile-water or methanol-water as the mobile phase, detected by UV detector (e.g., 254 nm), measure the main peak area to calculate purity (typically ≥98.0%). |
| Content (Main Component Quantification) | HPLC External Standard Method or Acid-Base Titration | HPLC method quantifies by comparison with reference standard; titration method may utilize its weak basicity for non-aqueous titration (less commonly used due to structural complexity). |
| Moisture | Karl Fischer Titration | Determine water content using either volumetric or coulometric Karl Fischer method, controlled within specified limits (e.g., ≤1.0%). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection to detect organic solvents possibly remaining from synthesis (e.g., dichloromethane, acetonitrile, DMF, etc.). |
| Inorganic Impurities (e.g., Fluoride Ion) | Ion Chromatography (IC) or Fluoride Ion Selective Electrode | Detect fluoride ions generated from degradation of tetrafluoroborate moiety, assessing product stability and inorganic salt residue. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range (TBTU typical melting point around 125–128°C), used as a supplementary indicator for identification and purity assessment. |
| pH Value (Solution) | pH Meter Measurement | Dissolve the sample in water at a specified concentration (e.g., 1%), then measure pH to evaluate acidity/alkalinity and possible degradation. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Use gradient elution program to separate and detect process impurities and degradation products; individual impurities usually controlled at ≤0.5%, total impurities ≤1.0%. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain characteristic absorption peaks (e.g., C=O, N=N, B-F), used for structural confirmation and batch-to-batch consistency comparison. |
| Test Item | Specification |
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| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.