RINK AMIDE LINKER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 126828-35-1 |
| Product name | RINK AMIDE LINKER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for RINK AMIDE LINKER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk RINK AMIDE LINKER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of RINK AMIDE LINKER
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Used in solid-phase peptide synthesis to prepare modified peptides containing tyrosine analogues, serving as a cleavable linker for tyrosine side-chain protection | Applied in Fmoc-based solid-phase peptide synthesis (SPPS) as a functionalized resin linker molecule: the phenoxyacetic acid moiety is coupled to polystyrene resin, while the Fmoc-amino group provides the amide bond attachment site for the first amino acid; the 2,4-dimethoxyphenyl group enhances acid stability and enables selective cleavage |
Manufacturing Quality Control of RINK AMIDE LINKER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265–280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and detection of structurally related impurities (e.g., FMOC-deprotected species, hydrolysis products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Identification and quantification of residual solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, Pd) after acid digestion, based on elemental mass-to-charge ratio detection. |
| Optical Purity (Chiral Impurity) | Chiral HPLC | Enantioselective separation using a chiral stationary phase and UV detection to assess enantiomeric excess or presence of racemized impurity. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave-assisted acid digestion, using atomic emission at characteristic wavelengths (e.g., 247.64 nm). |
| Particle Size Distribution | Laser Diffraction | Measurement of dry powder particle size distribution by analyzing angular scattering pattern of laser light passing through dispersed sample. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after controlled heating (105 °C, 2 h) under defined atmospheric conditions, indicating volatile content and residual solvents/moisture. |
| pH (1% w/v aqueous suspension) | Potentiometric pH Measurement | Determination of surface acidity/basicity via calibrated pH electrode in a standardized aqueous suspension, reflecting ionic impurities or degradation. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following USP <61> and <62>. |
Technical Specifications of RINK AMIDE LINKER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of RINK AMIDE LINKER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of RINK AMIDE LINKER
Packaging of RINK AMIDE LINKER
Industrial RINK AMIDE LINKER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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