Hydroxyurea Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 127-07-1 |
| Product name | Hydroxyurea |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Hydroxyurea
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Hydroxyurea Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Hydroxyurea
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Anticancer agent for treating chronic myeloid leukemia, melanoma, head and neck cancers, etc. | Acts as a ribonucleotide reductase inhibitor to disrupt DNA synthesis |
| Pharmaceuticals | Treatment of sickle cell anemia | Induces fetal hemoglobin (HbF) expression to reduce erythrocyte sickling |
| Pharmaceuticals | Antiviral research (e.g., adjunctive HIV therapy) | Inhibits nucleotide metabolism pathways involved in viral replication |
| Chemical Synthesis | Organic synthesis intermediate | Used in the synthesis of heterocyclic compounds, pyrimidine derivatives, etc. |
| Agricultural Research | Plant cell synchronization reagent | Inhibits DNA synthesis in root tip or callus tissue cells to achieve cell cycle synchronization |
Manufacturing Quality Control of Hydroxyurea
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference standard spectrum; confirm structure based on characteristic absorption peaks (e.g., N-H, C=O, O-H). |
| High-Performance Liquid Chromatography (HPLC) | Confirm consistency of the main peak by comparing retention time with a reference standard; used as an auxiliary identification method. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (approximately 210–220 nm); quantify hydroxyurea content by external standard or internal standard method. |
| Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measure concentration based on the characteristic absorbance of hydroxyurea at a specific wavelength (e.g., ~210 nm) using a standard calibration curve. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient elution; detect degradation products (e.g., urea, hydroxylamine); calculate individual impurity peak areas and control limits. |
| Water Content | Karl Fischer Titration | Precisely determine water content in the sample; suitable for quality control of active pharmaceutical ingredients. |
| Solution Clarity and Color | Visual Color Comparison | Dissolve the sample in water and compare visually with standard color reference solutions to determine whether the solution is clear and colorless or meets specified color requirements. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia) | Under weakly acidic conditions, heavy metals react with thioacetamide to form colored sulfides; perform a colorimetric limit test. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample to constant weight under specified temperature conditions; calculate the percentage weight loss to assess volatile component content. |
| Residue on Ignition | Ignition Method | Incinerate the sample at high temperature and weigh the residual residue to determine total inorganic impurities. |
| pH Value | pH Meter Method | Prepare a solution of hydroxyurea at a specified concentration and measure its acidity or alkalinity using a calibrated pH meter. |
Technical Specifications of Hydroxyurea
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 133–135°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Hydroxyurea
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Hydroxyurea
Packaging of Hydroxyurea
Industrial Hydroxyurea Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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