(R)-5,7-difluorochroman-4-ol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1270294-05-7 |
| Product name | (R)-5,7-difluorochroman-4-ol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-5,7-difluorochroman-4-ol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-5,7-difluorochroman-4-ol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-5,7-difluorochroman-4-ol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Catalytic hydrogenation, substitution reactions |
| Agrochemicals | Preparation of fluorinated agrochemical active ingredients | Alkylation, esterification |
| Materials Science | Functional polymer monomers | Condensation polymerization, copolymerization |
Manufacturing Quality Control of (R)-5,7-difluorochroman-4-ol
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible foreign matter under natural or standard lighting conditions. |
| Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Compare the sample spectrum with a reference standard; confirm functional groups and overall molecular structure consistency based on characteristic absorption peaks. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹⁹F-NMR) | Analyze the chemical environments of hydrogen and fluorine atoms using proton and fluorine NMR to verify stereochemistry and substitution patterns. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) with a UV detector to quantify the main component via external or internal standard methods. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employ a chiral stationary phase column to separate enantiomers, assess optical purity of the R-isomer, and detect S-isomer impurities. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient elution to detect organic impurities such as synthesis by-products and degradation products; require good separation between the main peak and impurity peaks. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying Method | Heat the sample at a specified temperature for a defined period and measure the percentage weight loss to estimate residual solvents or moisture content. |
| Water Content | Karl Fischer Titration | Use Karl Fischer reagent to accurately determine total water content (free and bound water), suitable for trace moisture analysis. |
| Residual Solvents | Gas Chromatography (GC) | Detect volatile organic solvents used during manufacturing (e.g., methanol, ethanol, acetone, dichloromethane) in accordance with ICH guidelines. |
| Melting Point | Capillary Melting Point Determination | Determine the temperature range over which the sample transitions from solid to liquid upon heating; used for preliminary assessment of purity and crystalline form consistency. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Analyze the crystal structure of solid samples to identify polymorphic forms and ensure batch-to-batch consistency in crystallinity. |
| Particle Size Distribution | Laser Diffraction Analysis (LDA) | Measure the particle size distribution of the active pharmaceutical ingredient, which influences dissolution rate and formulation performance, especially in oral solid dosage forms. |
Technical Specifications of (R)-5,7-difluorochroman-4-ol
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-5,7-difluorochroman-4-ol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-5,7-difluorochroman-4-ol
Packaging of (R)-5,7-difluorochroman-4-ol
Industrial (R)-5,7-difluorochroman-4-ol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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