1-methyl-1H-pyrazol-4-amine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 127107-23-7 |
| Product name | 1-methyl-1H-pyrazol-4-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-methyl-1H-pyrazol-4-amine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-methyl-1H-pyrazol-4-amine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-methyl-1H-pyrazol-4-amine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anticancer, antiviral, and kinase inhibitor compounds | Active molecular scaffolds are constructed via organic synthesis methods including nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of heterocyclic compounds with insecticidal or fungicidal activity | The pyrazolamine structural unit is introduced via diazotization, acylation, or cyclization |
| Fine Chemicals | Used as a functional material or ligand precursor in the synthesis of metal complexes or fluorescent probes | Coordination reactions with transition metals are performed utilizing the coordinating ability of both the amino group and the pyrazole ring |
Manufacturing Quality Control of 1-methyl-1H-pyrazol-4-amine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with the reference spectrum to confirm consistency in position and intensity of characteristic absorption peaks for functional groups (e.g., N–H, C=N, C–N) of 1-methyl-1H-pyrazol-4-amine. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Record the ¹H NMR spectrum of the sample in a deuterated solvent and compare chemical shifts, integration areas, and coupling constants to verify whether they match the structural characteristics of the target compound. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of an appropriate mixture of water and organic solvent (e.g., methanol or acetonitrile), and detect using a UV detector (typically around 254 nm). Quantify the main component using external or internal standard methods. |
| Related Substances / Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Similar conditions as assay, but with optimized gradient elution to effectively separate the main peak from potential impurities (e.g., starting materials, by-products, degradation products). Impurity levels are calculated using area normalization or relative response factors. |
| Water Content | Karl Fischer Titration | Quantitatively determine water content by reacting the sample with Karl Fischer reagent. Water is measured via volumetric or coulometric titration. Suitable for thermally unstable compounds. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, analyze residual organic solvents (e.g., methanol, dichloromethane, DMF) possibly remaining from synthesis on polar or non-polar capillary columns with an FID detector, following pharmacopoeial or ICH guidelines for qualitative and quantitative determination. |
| Melting Point | Capillary Melting Point Method | Pack dried sample into a melting point capillary tube and heat at a specified rate in a melting point apparatus. Observe and record the temperature range from initial melting to complete melting as an auxiliary indicator of purity and identity. |
| Appearance and Physical Characteristics | Visual Inspection | Observe the color, crystal form, odor, and other physical characteristics under natural light or standard illumination. The sample should appear as white to off-white crystalline powder, free from visible foreign matter or unusual odor. |
| pH Value (if dissolved in solution) | pH Meter Method | Prepare a solution of specified concentration (e.g., 1% w/v) and measure its pH using a calibrated pH meter to assess whether acidity or alkalinity meets quality specifications. |
Technical Specifications of 1-methyl-1H-pyrazol-4-amine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-methyl-1H-pyrazol-4-amine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-methyl-1H-pyrazol-4-amine
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Industrial 1-methyl-1H-pyrazol-4-amine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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