(R)-3-Aminopiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 127294-73-9 |
| Product name | (R)-3-Aminopiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-3-Aminopiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-3-Aminopiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-3-Aminopiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for antiviral, antitumor, and central nervous system (CNS) drugs (e.g., HIV integrase inhibitors) | Used as a chiral auxiliary or starting material in asymmetric synthesis, coupling reactions (e.g., Suzuki, Buchwald–Hartwig), and multistep total synthesis |
| Pharmaceutical R&D | Structural modification unit for highly selective targeting molecules, enhancing enantiomeric activity and metabolic stability of drug candidates | Introduces chiral aminopiperidine motifs during lead compound optimization, followed by derivatization via amidation, sulfonylation, or alkylation |
| Fine Chemicals | Precursor to chiral ligands or catalysts for preparing nitrogen-containing heterocyclic chiral catalysts | Processed through protection/deprotection and functional group transformation, then coordinated with metals (e.g., Pd, Rh) to form asymmetric catalytic systems |
Manufacturing Quality Control of (R)-3-Aminopiperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification of (R)-3-aminopiperidine enantioselectively using a chiral stationary phase and UV detection. |
| Enantiomeric Excess (ee) | Chiral HPLC | Comparison of peak areas of (R) and (S) enantiomers to calculate enantiomeric excess based on chiral resolution. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and pyridine in methanol to determine trace water content. |
| Residual Solvents | Gas Chromatography (GC) | Separation and quantification of volatile organic solvents by capillary GC with FID or MS detection. |
| Heavy Metals | ICP-OES | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion via atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography (IC) | Quantitative determination of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfate Impurity | Ion Chromatography (IC) | Quantitative determination of sulfate ions using suppressed conductivity detection after anion exchange separation. |
| Related Substances | HPLC with UV Detection | Separation and quantification of structurally related impurities using reversed-phase HPLC and UV absorbance. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated apparatus to detect solid-to-liquid phase change range. |
| Residue on Ignition | Gravimetric Analysis | Determination of non-volatile inorganic residue after high-temperature ashing and weighing. |
Technical Specifications of (R)-3-Aminopiperidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (by NMR) |
| Optical Rotation | +3.5 to +4.5 deg (c=1, in MeOH) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62 to 66 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-3-Aminopiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-3-Aminopiperidine
Packaging of (R)-3-Aminopiperidine
Industrial (R)-3-Aminopiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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