N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 127346-48-9 |
| Product name | N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Serving as a key intermediate in the synthesis of peptide-based drugs (e.g., octreotide acetate) | Solid-phase peptide synthesis (SPPS) or solution-phase synthesis to incorporate the 1,3-diaminopropane moiety into the peptide chain |
| Pharmaceutical Chemicals | Synthesizing active pharmaceutical ingredients (APIs) and bioactive molecules containing diamine structures | Deprotection of the BOC group to activate the amino group, followed by coupling with carboxylic acid derivatives |
| Organic Synthesis | Constructing macrocyclic or heterocyclic compounds (e.g., piperazine derivatives) | Cyclization or nucleophilic substitution reactions leveraging the bifunctional amino groups |
| Drug Discovery | High-throughput screening and structure–activity relationship (SAR) studies | Incorporated as a building block into lead compounds to optimize pharmacokinetic properties |
| Biochemistry | Synthesizing biotin, fluorescent labeling reagents, and DNA intercalators | Multi-step synthesis utilizing primary amino groups for specific conjugation and labeling |
Manufacturing Quality Control of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 200–220 nm, comparing peak area against a certified reference standard. |
| Water Content | Karl Fischer Titration | Electrochemical titration based on the stoichiometric reaction of iodine with water in a methanol-based reagent. |
| Residual Solvents (e.g., THF, MeOH, DCM) | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection using internal standard calibration. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification via inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Chloride Ion (Cl⁻) Content | Ion Chromatography (IC) | Anion separation on a high-capacity suppressor column with conductivity detection, calibrated against NaCl standards. |
| Related Substances | HPLC-UV/DAD | Identification and quantification of structurally related impurities (e.g., N-BOC-propanediamine isomers, de-BOC product) using gradient HPLC with diode array detection. |
| Residual BOC Anhydride | GC-MS | Detection and quantification of di-tert-butyl dicarbonate by capillary GC coupled to electron ionization mass spectrometry. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in aqueous suspension after equilibration. |
| Melting Point | DSC | Thermal transition analysis by differential scanning calorimetry under controlled nitrogen purge to determine onset and range of melting. |
| Appearance & Color | Visual Inspection / Hazen/APHA Color Scale | Subjective visual assessment against white background; color quantified by comparison to platinum-cobalt standard solutions. |
| Residue on Ignition | Gravimetric Analysis | Mass loss upon high-temperature ashing (550–600 °C) followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | [α]D | Measurement of specific rotation using sodium D-line (589 nm) in specified solvent (e.g., water or methanol) at controlled temperature and concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser light scattering to determine volume-based particle size distribution (D10, D50, D90). |
Technical Specifications of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145°C - 152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
Packaging of N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE
Industrial N-BOC-1,3-DIAMINOPROPANE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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