China Factory Direct
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| CAS number | 127423-61-4 |
| Product name | ethyl 2-chloro-4-ethoxy-nicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 5KG/bag25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate | Used to synthesize optically active drug molecules, such as certain antiviral or cardiovascular therapeutics |
| Chemical Research | Ligand for chiral catalysts | Serves as a chiral induction source in asymmetric catalytic reactions to achieve high enantioselectivity |
| Organic Synthesis | Critical step in synthesizing complex organic compounds | Constructs target molecules containing a pyrrolidine scaffold via substitution reactions with various nucleophiles |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using UV detection at specified wavelength with external standard calibration. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase with UV detection to determine (R)-enantiomer excess. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion. |
| Residual BOC Reagent | GC-MS | Detection and quantification of di-tert-butyl dicarbonate and its degradation products by mass-selective detection. |
| Residual Methanesulfonic Acid | Ion Chromatography | Separation and conductivity detection of methanesulfonate anion in aqueous extract. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via light scattering pattern measurement. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by controlled heating and visual observation of solid-to-liquid phase change. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral integrity and concentration. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave-assisted digestion and plasma emission detection. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -26.0 to -25.5 deg (c=1, CHCl3) |
| Melting Point | 72.0 to 76.0 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.