(1S,2R)-N-TOSYLEPHEDRINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 127641-25-2 |
| Product name | (1S,2R)-N-TOSYLEPHEDRINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (1S,2R)-N-TOSYLEPHEDRINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (1S,2R)-N-TOSYLEPHEDRINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (1S,2R)-N-TOSYLEPHEDRINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral auxiliary or chiral resolving agent for synthesizing optically active pharmaceutical intermediates | Used as a chiral ligand or catalyst component in asymmetric synthesis, enabling metal-catalyzed C–C bond formation reactions (e.g., allylation, alkylation) |
| Pharmaceuticals | The (1R,2S)-enantiomer serves as a key chiral building block for structural optimization of antidepressants and β-blocker analogues | Prepared via chiral chromatographic resolution or enzymatic kinetic resolution to achieve high enantiomeric purity, followed by protection and functional group transformations to incorporate into the target molecular scaffold |
Manufacturing Quality Control of (1S,2R)-N-TOSYLEPHEDRINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separates (1R,2S) and (1S,2R) enantiomers on a chiral stationary phase and calculates ee from peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., ethanol, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elements such as Pb, Cd, Hg, and As at sub-ppb levels using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., starting materials, intermediates, degradants) using gradient HPLC. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm stereochemical identity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating purity and identity. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residue. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser light. |
Technical Specifications of (1S,2R)-N-TOSYLEPHEDRINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +15.1 to +15.7 (c=1, in methanol) |
| Melting Point | 62.0 to 66.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (1S,2R)-N-TOSYLEPHEDRINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (1S,2R)-N-TOSYLEPHEDRINE
Packaging of (1S,2R)-N-TOSYLEPHEDRINE
Industrial (1S,2R)-N-TOSYLEPHEDRINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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