China Factory Direct
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| CAS number | 127666-99-3 |
| Product name | 2-CHLORO-4-METHOXYBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the herbicide clopyralid | Used to prepare clopyralid via multi-step reactions including nitration, reduction, diazotization, cyanation, and methylation |
| Pharmaceuticals | Structural building block for antitumor agents and kinase inhibitors | Employed as an aryl substitution module in coupling reactions (e.g., Suzuki, Heck) to construct targeted molecular scaffolds |
| Materials Science | Monomer for electron-transport materials in organic light-emitting diodes (OLEDs) | Incorporated into nitrile-containing conjugated backbones via halogen exchange or metal-catalyzed polymerization to enhance electron affinity and thermal stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and detector. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities by retention time and UV absorbance relative to the main peak. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling and FID detection | Volatile organic solvents are extracted in headspace vial and quantified by comparing peak areas to calibration standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water; endpoint detected amperometrically. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Anionic impurities separated on an ion-exchange column and quantified by conductivity response relative to chloride standard. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Elemental analysis after acid digestion; metals atomized and excited in plasma, emitting element-specific wavelengths measured optically. |
| Residue on Ignition | Gravimetric analysis (Sulfated Ash method) | Sample ignited at 700-800 C after sulfuric acid treatment; non-volatile residue weighed to determine inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid transforms to liquid under controlled heating rate. |
| Appearance | Visual Inspection (in solution and neat) | Assessment of physical state, color, and clarity against standard references under controlled lighting and conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; indicates chiral purity if applicable. |
| pH of Aqueous Suspension | pH Meter measurement | Electrochemical measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Analysis of light scattering pattern from dispersed particles to calculate size distribution based on Mie or Fraunhofer theory. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.